Protein Alignment Grip75 and LOC1276259

DIOPT Version :10

• Sequence 1: NP_609412.1
• Gene: Grip75 / 34441
• FlyBaseID: FBgn0026431
• Length: 650
• Species: Drosophila melanogaster
• Sequence 2: XP_061505472.1
• Gene: LOC1276259 / 1276259
• VectorBaseID: AGAMI1_013802
• Length: 914
• Species: Anopheles gambiae
• Alignment Length: 710
• Identity: 157/710 - (22%)
• Similarity: 275/710 - (38%)
• Gaps: 163/710 - (22%)

  Fly    24 ETTVIDQFIHPCEREIFMDIIKIIKVYQEVEQFTHSSGRKSDTHGELPDSLHGYYLLNLAKGIEM 88
            |..:.:|....| |::.::::.:...|..|:.|...:   |.|.|       |..|..|...::.
Mosquito   279 EFQLSNQLTESC-RDMVVEVLPLAANYSAVQSFIEGA---SVTEG-------GVVLQALRSVLKT 332

  Fly    89 ALEEYYAEIGRLEKYCLGNERN-SLSYVYNALYAKFPLLVFMRNLITEIHVLNLRGCVLLHNLHQ 152
            .:.:||..|.:|:.  |...|. ||..:...|...:|.:..:...::||...|.||..:|..||.
Mosquito   333 IMTDYYLSIAQLDD--LRCRRGLSLQRLIQFLKPVYPTMEELAATVSEIRRSNARGGQVLSLLHD 395

  Fly   153 Q--CEHGDIQLEKAIKIIMKPVKNAFFSSLAHWLLFGVIDDVHSEFFIKFTPTDAVDGSSFSKSA 215
            :  .:.|....:|.:..:::.....|...|..|:..|||:|...||||        |.||...:
Mosquito   396 RITAKSGTNHAQKVLVHLVESAAAPFMEMLELWIYRGVINDPQQEFFI--------DHSSMELT- 451

  Fly   216 TCSLLSAEKNPEDYIW--QYEVNMSQLPGFFSIVLAEKVLFVGQTVLVFKM-------------G 265
                   |....|| |  ||.:...::|.|.: ..|:.:|..|:.:.|.::             |
Mosquito   452 -------ENELVDY-WEKQYTIRNEKVPCFLA-KHADIILRTGKYLNVVRVCGGAEFQPGNANGG 507

  Fly   266 RNVKVKNKTDPLAAKLAELDSDDIYQLWSGRESEFFKMV----VDLSNEDTINVFRLEKVIIDIK 326
            ........||.|.|..|           :.|.:...|.:    .|.|..|.|.         :..
Mosquito   508 GGGGATTTTDLLNASSA-----------TARTTTAVKRLQYAHFDQSYLDEIE---------EAY 552

  Fly   327 NYVSARLSEIAVNEVDLERQMGLIKDFFLLGRGEFYLEFCSQMVGTMETYREERFKNV-----TR 386
            |:.|:.|..:.:|:.||..::..:|.:|||.:|:|..||       |:...|:..|:|     .|
Mosquito   553 NFASSSLLNLIMNKYDLMGRLLSVKRYFLLQQGDFITEF-------MDAVEEDLRKSVDTLHPIR 610

  Fly   387 SFELAATVTGIT--------DDL----------DKFSLICQRSTSEPDDTSDFNFLQGL---SLK 430
            ...|.....|::        |||          .:.|.|.....:..|..||.:.|:|:   :..
Mosquito   611 LANLLDVTLGLSSAKYDEYHDDLKTMLLPYGIVTQISKIVNNEDAFVDTLSDTSQLKGVECFTFT 675

  Fly   431 YEYEWPLNLLFSPTTIERYNNIFRFLLIIRTYQYEIQRVWAKQTWRAKSAKDVPPN-----NKII 490
            |:.:||::::.:..||.:|..|||.|..::..:..:.|||...    ...:...||     ....
Mosquito   676 YKAQWPVSIVLNLWTISKYQMIFRQLFYLKYVERILCRVWIAN----NETRQFAPNPAKLYRSAF 736

  Fly   491 TLRNYLMFFLNNMQYYIQVDVLESQFGILMNVIKSRSDFEVIQRAHTVFLANVLSHCFLLNESET 555
            |||..::..:.:.:.|:.::|:|..:.|....:|...:.:.:...|..||...|.:|.|   :|.
Mosquito   737 TLRQKMLIAIQSFESYMMIEVIEPNWHIFYQNMKQVKNIDDVLNYHQDFLDQCLKNCML---TEP 798

  Fly   556 QLNVTGSQNRNPIYGTLLKLFGICEKF-------------AHMT--------------------- 586
            .|       ..||    :.|..||.||             |.:|
Mosquito   799 DL-------LKPI----INLCNICIKFCDFLAESQRHFVDAELTCMLASGDDCSLSSESDYEQTA 852

  Fly   587 QTKDPSDDLEDEVDQLNESFGVQIASLIQLLVDVKSASCLGPLSQLLLRLDFNCWFSASH 646
            .|..|::...:.|:|....|..|:.:|::.:.||.:.|.......|:.|::||.::|.::
Mosquito   853 TTMAPTETFSERVEQFRHDFTDQLMTLLRKIADVATLSTSERFINLIYRINFNSYYSETN 912

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grip75	NP_609412.1	GCP_N_terminal	2..340	CDD:465456	74/337 (22%)
		GCP_C_terminal	349..642	CDD:461187	79/357 (22%)
LOC1276259	XP_061505472.1	None