Protein Alignment RluA-2 and RPUSD2

DIOPT Version :10

• Sequence 1: NP_609411.1
• Gene: RluA-2 / 34440
• FlyBaseID: FBgn0032256
• Length: 547
• Species: Drosophila melanogaster
• Sequence 2: NP_689473.1
• Gene: RPUSD2 / 27079
• HGNCID: 24180
• Length: 545
• Species: Homo sapiens
• Alignment Length: 551
• Identity: 230/551 - (41%)
• Similarity: 314/551 - (56%)
• Gaps: 81/551 - (14%)

  Fly     7 LRNAQTQHGDA-SSVDVENIFLHRHMLYTNPTSDGNLHDREDSPECVWCPDDKDGSPAESKDPPI 70
            ||.:..|:||| ....||        |...|.....   ||..|..|........:|...|.
Human    49 LRASHQQNGDAGGDAKVE--------LSPGPPKPAG---REVEPAPVGGEHPSAAAPGPGKH--- 99

  Fly    71 SISEEKSETQSKEVLSEKRKASSTDDEGHVKKVKLEANSLKTKRPGFSDERYDETSYYFENGLRK 135
              .:.:..|:.:.|...|::.:..                     .|.||.:.|||||||.||||
Human   100 --KKRRGATRERVVPPPKKRRTGV---------------------SFGDEHFAETSYYFEGGLRK 141

  Fly   136 VYPYFFTFTTFAKGRWVDEKILDVFVREFRAAPPEEYERSLEAGKLTVNSEKVPKDYKI--KHND 198
            |.||:|.|.|:.|||||...:|.||..||||.|...||.::.||:|.:| ||..:|..|  |.||
Human   142 VRPYYFDFRTYCKGRWVGHSLLHVFSTEFRAQPLAYYEAAVRAGRLQLN-EKPVQDLNIVLKDND 205

  Fly   199 LLANVVHRHEVPVTSQPIKIVYMDKDIVVVNKPASIPVHPCGRYRHNTVVFILAKEHNLKNLRTI 263
            .|.|.|||||.|||::||:::..::|:|||:||:|||||||||:|||||:|||.|||.||.|..:
Human   206 FLRNTVHRHEPPVTAEPIRLLAENEDVVVVDKPSSIPVHPCGRFRHNTVIFILGKEHQLKELHPL 270

  Fly   264 HRLDRLTSGLLLFGRTAEKARELELQIRTRQVQKEYVCRVEGRFPDGIVECNEKIDVVSYKIGVC 328
            |||||||||:|:|.:||..:..:..|:|.||::|||||||||.||...|.|.|.|.|||||:|||
Human   271 HRLDRLTSGVLMFAKTAAVSERIHEQVRDRQLEKEYVCRVEGEFPTEEVTCKEPILVVSYKVGVC 335

  Fly   329 KVSPKGKDCKTTFKRIGEVGSDSIVLCKPLTGRMHQIRVHLQFLGYPISNDPLYNHEVFGPLKGR 393
            :|.|:||.|:|.|:|:...|..|:|.|:|||||.|||||||||||:||.|||:||...:||.:||
Human   336 RVDPRGKPCETVFQRLSYNGQSSVVRCRPLTGRTHQIRVHLQFLGHPILNDPIYNSVAWGPSRGR 400

  Fly   394 GGDIGGITEEQLISNLISIHNAENWLGL----EGD-------------QIVSGEIKDVAASTSVV 441
            ||.|.. |.|:|:.:|::.|.|:..|.:    |||             ::...:::::||:...:
Human   401 GGYIPK-TNEELLRDLVAEHQAKQSLDVLDLCEGDLSPGLTDSTAPSSELGKDDLEELAAAAQKM 464

  Fly   442 EAPSVVQAPINSETEKPVISKNLEPSNDATAQIATQTCYEEPDRSFDSKKTTSDPQCSECKINYR 506
            |  .|.:|               .|....|..:|::...|.     |.....:||.|:||::..:
Human   465 E--EVAEA---------------APQELDTIALASEKAVET-----DVMNQETDPLCAECRLVRQ 507

  Fly   507 DPGTKDLIMYLHAWKYKGVGWEYETELPEWA 537
            ||..:||:|:|||.:|||.|:||.:.:|.||
Human   508 DPLPQDLVMFLHALRYKGPGFEYFSPMPAWA 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RluA-2	NP_609411.1	PseudoU_synth_ScRIB2	202..386	CDD:211331	115/183 (63%)
RPUSD2	NP_689473.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	48..121		19/87 (22%)
		PseudoU_synth_ScRIB2	208..391	CDD:211331	114/182 (63%)