DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RluA-1 and PUS5

DIOPT Version :9

Sequence 1:	NP_723592.1	Gene:	RluA-1 / 34438	FlyBaseID:	FBgn0051719	Length:	739	Species:	Drosophila melanogaster
Sequence 2:	NP_013266.1	Gene:	PUS5 / 850862	SGDID:	S000004155	Length:	254	Species:	Saccharomyces cerevisiae

Alignment Length:	230	Identity:	62/230 - (26%)
Similarity:	101/230 - (43%)	Gaps:	63/230 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   377 IKIVHMDEDIVVVNKPASIPVHP--C---GRYRHN----------TVVFILAKEFNLKNLRTIHR 426
            |.|:..:....:||||..||..|  |   ||...|          ..::...:|..|  .||:||
Yeast     7 IPIIFENTHYFIVNKPPGIPSQPPDCRTWGRTHPNLDPTPLLERFKAIYYSHREVEL--CRTVHR 69

  Fly   427 LDRLTSGLLLFGR----SPKKARQMEQQIRN-RQVEKEYICRVE--GVF--PDGIVECKEPIEVV 482
            ||...:|.:|..:    |.|.:|.:::...| .:::::|:..||  |.|  |:
Yeast    70 LDHCVTGGMLIAKTKDGSVKFSRFLQKGGNNGYKLQRKYVAIVESSGRFNKPN------------ 122

  Fly   483 SYKIGV-----CKVSAKGKDCTTTFQKLSQNGTTSVVLCKPLTGRMHQIRVHL-QYLGYPILNDP 541
            :|:|..     ..:|..|:: .|.|:::.:|    .::.:.:||:.||||.|: |.|..|||||.
Yeast   123 NYEIKYGPKYNFLISHGGRE-ITKFKEVDEN----CIVLQLVTGKKHQIRNHVSQILNQPILNDK 182

  Fly   542 LYNHEVFGPLKGRSGDIGGKSDEELIRDLINIHNA 576
            .:...|..|              ||..|.|.:|:|
Yeast   183 RHGSTVNFP--------------ELFNDQIALHSA 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RluA-1	NP_723592.1	Auts2	21..>162	CDD:291981
RluA-1	NP_723592.1	PseudoU_synth_ScRIB2	363..547	CDD:211331	54/199 (27%)
PUS5	NP_013266.1	RluA	<4..205	CDD:223638	62/230 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0564
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810