DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RluA-1 and RPUSD4

DIOPT Version :9

Sequence 1:	NP_723592.1	Gene:	RluA-1 / 34438	FlyBaseID:	FBgn0051719	Length:	739	Species:	Drosophila melanogaster
Sequence 2:	NP_116184.2	Gene:	RPUSD4 / 84881	HGNCID:	25898	Length:	377	Species:	Homo sapiens

Alignment Length:	218	Identity:	66/218 - (30%)
Similarity:	105/218 - (48%)	Gaps:	44/218 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   357 HNDLLANIVHRHEVPVTCQPIKIVHMDEDIVVVNKPASIPVH--PCGRYRHNTVVFILAKEFN-- 417
            |.::||..:.|          .|:|.|:::||:|||..:|||  |..:.....|:.||||..:
Human    87 HPNVLAKALTR----------GILHQDKNLVVINKPYGLPVHGGPGVQLCITDVLPILAKMLHGH 141

  Fly   418 -LKNLRTIHRLDRLTSGLLLFGRSPKKARQMEQQIRNRQVEKEY-ICRVEGVFPD-GIVECKEPI 479
             .:.|...||||:.|:|:::.......|.|:::..|.|||.|:| ...|....|. |:|:    |
Human   142 KAEPLHLCHRLDKETTGVMVLAWDKDMAHQVQELFRTRQVVKKYWAITVHVPMPSAGVVD----I 202

  Fly   480 EVV-----------------SYKIGVCKV-----SAKGKDCTTTFQKLSQNGTTSVVLCKPLTGR 522
            .:|                 ||::...|:     |...:...|.:|.||...::::|..:|:||.
Human   203 PIVEKEAQGQQQHHKMTLSPSYRMDDGKMVKVRRSRNAQVAVTQYQVLSSTLSSALVELQPITGI 267

  Fly   523 MHQIRVHLQY-LGYPILNDPLYN 544
            .||:||||.: |..|||.|..|:
Human   268 KHQLRVHLSFGLDCPILGDHKYS 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RluA-1	NP_723592.1	Auts2	21..>162	CDD:291981
RluA-1	NP_723592.1	PseudoU_synth_ScRIB2	363..547	CDD:211331	63/212 (30%)
RPUSD4	NP_116184.2	PseudoU_synth_RluCD_like	106..329	CDD:211346	59/189 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0564
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810