DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment RluA-1 and rpusd1

DIOPT Version :9

Sequence 1:	NP_723592.1	Gene:	RluA-1 / 34438	FlyBaseID:	FBgn0051719	Length:	739	Species:	Drosophila melanogaster
Sequence 2:	NP_001070221.1	Gene:	rpusd1 / 767786	ZFINID:	ZDB-GENE-060929-444	Length:	293	Species:	Danio rerio

Alignment Length:	337	Identity:	77/337 - (22%)
Similarity:	122/337 - (36%)	Gaps:	84/337 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   371 PVTCQPIKIVHMDEDIVVVNKPASIPVHPCGRYRHNTVVFILAKEF-------NLKNLRTIHRLD 428
            |.:.:.:.:::...:.:||||...|.:.....|...||...|...|       .....|..|:||
Zfish     3 PASLENLSVLYQSTNYIVVNKHWDIRIDSKMWYEKQTVQSQLKHHFPELADPGTYYGFRFCHQLD 67

  Fly   429 RLTSGLLLFGRSPKKARQMEQQIRNRQVEKEYICRVEGVFPDGIVECKEPIEVVSYKIG------ 487
            ..|||.|....:...|.|..:..::|:|.|.|:..|.|...:..:.       :.:.||
Zfish    68 FSTSGALCVALNKAAAGQAYRCFKDRRVTKAYLALVRGTVTEENLS-------LDFAIGKNTTEG 125

  Fly   488 ----VCKVSAKG----KDCTTTFQKLSQNGT-----TSVVLCKPLTGRMHQIRVHLQYLGYPILN 539
                :|....:|    |.|.|....| :.||     .:.||.:|||||.||:|||...:|:||:.
Zfish   126 KTHMMCTEGTEGCENPKPCQTEVTVL-EYGTYDGDQVTKVLLQPLTGRTHQLRVHCSAIGHPIVG 189

  Fly   540 DPLYNHEVFGPLKGRSGDIGGKSDEELIRDLINIHNAENWLGIDCDSDISMFKSTKDEADRESLS 604
            |..|:.               ::|....|.:::.:    :|.|..
Zfish   190 DYTYSL---------------RTDNSPYRMMLHAY----FLHIPL-------------------- 215

  Fly   605 SEHTSVVHHSDDDGCVNSRETTPPCNEPQQPENSVKLLE--TTNAVKEYQVAAQKSSSEICPAPL 667
              |...:|.:..|..|      |..:....|...|.:||  ..|.:.:.| ||.:..:|..|...
Zfish   216 --HNEPIHVTAPDPFV------PSLDAKWAPLRCVNILEDLLKNILTKLQ-AAMQEEAEPEPRTS 271

  Fly   668 DAVESPLNGGGC 679
            ..|||......|
Zfish   272 SPVESEEQRAQC 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RluA-1	NP_723592.1	Auts2	21..>162	CDD:291981
RluA-1	NP_723592.1	PseudoU_synth_ScRIB2	363..547	CDD:211331	54/201 (27%)
rpusd1	NP_001070221.1	RluA	<9..228	CDD:223638	60/267 (22%)
rpusd1	NP_001070221.1	PseudoU_synth_RluCD_like	18..213	CDD:211346	56/221 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0564
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D504187at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100211
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.720