DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RluA-1 and RPUSD3

DIOPT Version :9

Sequence 1:	NP_723592.1	Gene:	RluA-1 / 34438	FlyBaseID:	FBgn0051719	Length:	739	Species:	Drosophila melanogaster
Sequence 2:	NP_775930.3	Gene:	RPUSD3 / 285367	HGNCID:	28437	Length:	343	Species:	Homo sapiens

Alignment Length:	251	Identity:	58/251 - (23%)
Similarity:	99/251 - (39%)	Gaps:	57/251 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   360 LLANIVHRHEVPVTCQPIKIVHMDEDIVVVNKPASIPVHPCGRYRHNTVVFI---LAKEFNLK-- 419
            ||...:.|.|: |......:|.....:|.:|||..:||  .|:....|:..:   |::...|:
Human    57 LLPKNLSREEL-VDALRAAVVDRKGPLVTLNKPQGLPV--TGKPGELTLFSVLPELSQSLGLREQ 118

  Fly   420 NLRTIHRLDRLTSGLLLFGRSPKKARQMEQ---QIRNRQVEKEYICRVEGVFP------------ 469
            .|:.:....:.:|||:|....|:.|.::::   ..|..|......|.|....|
Human   119 ELQVVRASGKESSGLVLLSSCPQTASRLQKYFTHARRAQRPTATYCAVTDGIPAASEGKIQAALK 183

  Fly   470 ----DGI---VECKEP-----IEVVSYKIGVCKVSAKGKDCTTTFQKLSQNGTTSVVLCKPLTGR 522
                ||:   |..|.|     :|.|...:...:|.|.|..|             ::|..:|||..
Human   184 LEHIDGVNLTVPVKAPSRKDILEGVKKTLSHFRVVATGSGC-------------ALVQLQPLTVF 235

  Fly   523 MHQIRVHLQYLGYPILNDPLYNHEVFGPLKGRSGDIGGKS--------DEELIRDL 570
            ..|::||:.....|:|.|.:|:..| |.:.|:...:..::        ||.|:|.|
Human   236 SSQLQVHMVLQLCPVLGDHMYSARV-GTVLGQRFLLPAENNKPQRQVLDEALLRRL 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RluA-1	NP_723592.1	Auts2	21..>162	CDD:291981
RluA-1	NP_723592.1	PseudoU_synth_ScRIB2	363..547	CDD:211331	48/215 (22%)
RPUSD3	NP_775930.3	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0564
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810