Protein Alignment RluA-1 and RPUSD2

DIOPT Version :10

• Sequence 1: NP_723592.1
• Gene: RluA-1 / 34438
• FlyBaseID: FBgn0051719
• Length: 739
• Species: Drosophila melanogaster
• Sequence 2: NP_689473.1
• Gene: RPUSD2 / 27079
• HGNCID: 24180
• Length: 545
• Species: Homo sapiens
• Alignment Length: 547
• Identity: 241/547 - (44%)
• Similarity: 321/547 - (58%)
• Gaps: 96/547 - (17%)

  Fly   211 SPAPPLPAIQVL---------PSAEVPINKKTTSPRDSENLKIKVPEKRKTDDNDQIKELKKAKL 266
            ||.||.||.:.:         |||..|...|....|.:...::..|.|:
Human    68 SPGPPKPAGREVEPAPVGGEHPSAAAPGPGKHKKRRGATRERVVPPPKK---------------- 116

  Fly   267 ETKALKAKRPG--FTDERYQETSYYMENGLRKVYPYYFTFTTFTKGRWVGEKILDIFSREFRAHP 329
                   :|.|  |.||.:.|||||.|.|||||.||||.|.|:.||||||..:|.:||.||||.|
Human   117 -------RRTGVSFGDEHFAETSYYFEGGLRKVRPYYFDFRTYCKGRWVGHSLLHVFSTEFRAQP 174

  Fly   330 AEEYERCIQTGTLTVNFEKV-PIDYRLKHNDLLANIVHRHEVPVTCQPIKIVHMDEDIVVVNKPA 393
            ...||..::.|.|.:|.:.| .::..||.||.|.|.|||||.|||.:||:::..:||:|||:||:
Human   175 LAYYEAAVRAGRLQLNEKPVQDLNIVLKDNDFLRNTVHRHEPPVTAEPIRLLAENEDVVVVDKPS 239

  Fly   394 SIPVHPCGRYRHNTVVFILAKEFNLKNLRTIHRLDRLTSGLLLFGRSPKKARQMEQQIRNRQVEK 458
            |||||||||:|||||:|||.||..||.|..:|||||||||:|:|.::...:.::.:|:|:||:||
Human   240 SIPVHPCGRFRHNTVIFILGKEHQLKELHPLHRLDRLTSGVLMFAKTAAVSERIHEQVRDRQLEK 304

  Fly   459 EYICRVEGVFPDGIVECKEPIEVVSYKIGVCKVSAKGKDCTTTFQKLSQNGTTSVVLCKPLTGRM 523
            ||:|||||.||...|.|||||.|||||:|||:|..:||.|.|.||:||.||.:|||.|:|||||.
Human   305 EYVCRVEGEFPTEEVTCKEPILVVSYKVGVCRVDPRGKPCETVFQRLSYNGQSSVVRCRPLTGRT 369

  Fly   524 HQIRVHLQYLGYPILNDPLYNHEVFGPLKGRSGDIGGKSDEELIRDLINIHNAENWLGI-D-CDS 586
            ||||||||:||:||||||:||...:||.:||.|.| .|::|||:|||:..|.|:..|.: | |:.
Human   370 HQIRVHLQFLGHPILNDPIYNSVAWGPSRGRGGYI-PKTNEELLRDLVAEHQAKQSLDVLDLCEG 433

  Fly   587 DISMFKSTKDEADRESLSSEHTSVVHHSDDDGCVNSRETTPPCNEPQQPENSVKLLETTNAVKEY 651
            |:|                           .|..:|   |.|.:|..:.:           ::|.
Human   434 DLS---------------------------PGLTDS---TAPSSELGKDD-----------LEEL 457

  Fly   652 QVAAQKSS--SEICPAPLD--------AVESPLNGGGCNVGKVTVDEHCYECKVHYRDPKSKDLI 706
            ..||||..  :|..|..||        |||:       :|.....|..|.||::..:||..:||:
Human   458 AAAAQKMEEVAEAAPQELDTIALASEKAVET-------DVMNQETDPLCAECRLVRQDPLPQDLV 515

  Fly   707 MYLHAWKYKGPGWEYETELPNWARNDW 733
            |:|||.:|||||:||.:.:|.||::||
Human   516 MFLHALRYKGPGFEYFSPMPAWAQDDW 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RluA-1	NP_723592.1	PseudoU_synth_ScRIB2	363..547	CDD:211331	118/183 (64%)
RPUSD2	NP_689473.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	48..121		15/75 (20%)
		PseudoU_synth_ScRIB2	208..391	CDD:211331	117/182 (64%)