DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RluA-1 and SPAC18B11.02c

DIOPT Version :9

Sequence 1:	NP_723592.1	Gene:	RluA-1 / 34438	FlyBaseID:	FBgn0051719	Length:	739	Species:	Drosophila melanogaster
Sequence 2:	NP_592881.1	Gene:	SPAC18B11.02c / 2542607	PomBaseID:	SPAC18B11.02c	Length:	394	Species:	Schizosaccharomyces pombe

Alignment Length:	461	Identity:	163/461 - (35%)
Similarity:	244/461 - (52%)	Gaps:	87/461 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   272 KAKRPGFTDERYQETSYYMENGLRKVYPYYFTFTTFTKGRWVGEKILDIFSREFRAHPAEEYERC 336
            :.||....|..|    .:..:|||:|.|||:.:.||.|.||.|:.:|::|:.|||...:..||:.
pombe     4 RPKRDPLKDCEY----VFKGDGLRRVPPYYYEYITFAKLRWYGKTLLEVFNTEFRDRESGYYEKA 64

  Fly   337 IQTGTLTVNFEKVPIDYRLKHNDLLANIVHRHEVPVTCQPIKIVHMDEDIVVVNKPASIPVHPCG 401
            |:.|.:.||.:...:|..:::..::::..||||.||:.||:.|||.||..||::|||.:||||.|
pombe    65 IRNGQVKVNNQIGNVDTLIENGYIVSHHAHRHEPPVSDQPVGIVHEDESYVVIDKPAGVPVHPTG 129

  Fly   402 RYRHNTVVFILAKEFNLKNLRTIHRLDRLTSGLLLFGRSPKKARQMEQQIRNRQVEKEYICRVEG 466
            ||.||||:.||.||.....|...:|||||||||:.|.:|||.|.:|...:.::.::|||:.||.|
pombe   130 RYNHNTVLHILMKENKCSLLYPCNRLDRLTSGLMFFSKSPKAAEEMRVHMISKSLKKEYVARVIG 194

  Fly   467 VFPD-GIVECKEPIEVVSYKIGVCKVSAKGKDCTTTFQKLSQNGTTSVVLCKPLTGRMHQIRVHL 530
            .||: |.|.|..|:..|:..:|:.::...||:.:|.|::::.:|.||:|||||||||.||:||||
pombe   195 EFPNSGEVICDAPLLTVAPTLGLNRIHPDGKEASTVFKRIAFDGHTSLVLCKPLTGRTHQLRVHL 259

  Fly   531 QYLGYPILNDPLY-NHEVFGPLKGRSGDIGGKSDEELIRDLINIHNAENWLGIDCDSDISMFKST 594
            |||||||.|||:| |..|:||..|::|:   .|:|.:|..|..|...
pombe   260 QYLGYPIANDPIYANKRVWGPSLGKNGE---GSNESVIMRLSEIGKT------------------ 303

  Fly   595 KDEADRESLSSEHTSVVHHSDDDGCVNSRETTPPCNEPQQPENSVKLLETTNAVKEYQVAAQKSS 659
                                                            ||.:.:.:|:....::.
pombe   304 ------------------------------------------------ETASPLLQYEWYTNETE 320

  Fly   660 SEICPAPLDAVESPLNGGGCNVGKVTVDEHCYECKVH-YRDPKSKDLIMYLHAWKYKGPGWEYET 723
            :| ..|..|.          .:|::...:||.||... |.||..::|.::|||.||:...|.|:|
pombe   321 AE-AKARRDK----------RLGELLTGKHCSECGTPLYSDPSPEELGIWLHALKYESKDWSYKT 374

  Fly   724 ELPNWA 729
            :||.||
pombe   375 QLPKWA 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RluA-1	NP_723592.1	Auts2	21..>162	CDD:291981
RluA-1	NP_723592.1	PseudoU_synth_ScRIB2	363..547	CDD:211331	97/185 (52%)
SPAC18B11.02c	NP_592881.1	rluA_subfam	39..364	CDD:161659	140/404 (35%)
		PseudoU_synth_ScRIB2	90..380	CDD:211331	132/369 (36%)
		Auto_anti-p27	330..356	CDD:294466	8/25 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	150	1.000	Domainoid score	I1102
eggNOG	1	0.900	-	-		E1_COG0564
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I703
OMA	1	1.010	-	-		QHG51879
OrthoFinder	1	1.000	-	-		FOG0002443
OrthoInspector	1	1.000	-	-		otm47324
orthoMCL	1	0.900	-	-		OOG6_100211
Panther	1	1.100	-	-	LDO	PTHR21600
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1681
SonicParanoid	1	1.000	-	-		X1265
TreeFam	1	0.960	-	-
	13	12.860