DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment RluA-1 and RPUSD1

DIOPT Version :9

Sequence 1:	NP_723592.1	Gene:	RluA-1 / 34438	FlyBaseID:	FBgn0051719	Length:	739	Species:	Drosophila melanogaster
Sequence 2:	NP_001311015.1	Gene:	RPUSD1 / 113000	HGNCID:	14173	Length:	315	Species:	Homo sapiens

Alignment Length:	225	Identity:	57/225 - (25%)
Similarity:	84/225 - (37%)	Gaps:	55/225 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   371 PVTCQPIKIVHMDEDIVVVNKPASIPVHPCG-----------RYRHNTVVFILAKEFNLKNLRTI 424
            |.:.:.:.||:...|.:||||...:.:....           |||...    ||........|..
Human     3 PGSVENLSIVYRSRDFLVVNKHWDVRIDSKAWRETLTLQKQLRYRFPE----LADPDTCYGFRFC 63

  Fly   425 HRLDRLTSGLLLFGRSPKKARQMEQQIRNRQVEKEYICRVEGVFPDGIVECKEPIEVVSYKIG-- 487
            |:||..|||.|....:...|....:..:.|:|.|.|:..:.|       ..:|....:|:.||
Human    64 HQLDFSTSGALCVALNKAAAGSAYRCFKERRVTKAYLALLRG-------HIQESRVTISHAIGRN 121

  Fly   488 --------VCKVSAKG-----------KDCTTTFQKLSQNGTTSVVLCKPLTGRMHQIRVHLQYL 533
                    :|...::|           .|.......|......|.||.||||||.||:|||...|
Human   122 STEGRAHTMCIEGSQGVAGCENPKPSLTDLVVLEHGLYAGDPVSKVLLKPLTGRTHQLRVHCSAL 186

  Fly   534 GYPILNDPLYNHEVFGPLKGRSGDIGGKSD 563
            |:|::.|..|            |::.|:.|
Human   187 GHPVVGDLTY------------GEVSGRED 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RluA-1	NP_723592.1	Auts2	21..>162	CDD:291981
RluA-1	NP_723592.1	PseudoU_synth_ScRIB2	363..547	CDD:211331	54/207 (26%)
RPUSD1	NP_001311015.1	RluA	<9..233	CDD:223638	56/219 (26%)
		PseudoU_synth_RluCD_like	18..218	CDD:211346	53/210 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	259..301
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D504187at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100211
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820