DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RluA-1 and Rpusd3

DIOPT Version :9

Sequence 1:	NP_723592.1	Gene:	RluA-1 / 34438	FlyBaseID:	FBgn0051719	Length:	739	Species:	Drosophila melanogaster
Sequence 2:	NP_001028376.1	Gene:	Rpusd3 / 101122	MGIID:	2141440	Length:	344	Species:	Mus musculus

Alignment Length:	272	Identity:	61/272 - (22%)
Similarity:	102/272 - (37%)	Gaps:	81/272 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   356 KHNDL-------------------LANIVHRHEVPVTCQPIKIVHMDEDIVVVNKPASIPVHPCG 401
            ||.||                   ||:::.          ..:|.....:|.:|||..:||  .|
Mouse    44 KHKDLVEDQPFPGLLRTENLGLEELAHVLR----------AAVVDQKGPLVTLNKPQGLPV--TG 96

  Fly   402 RYRHNTVVFIL-----AKEFNLKNLRTIHRLDRLTSGLLLFGRSPKKARQMEQ-QIRNRQVEK-- 458
            |....|::.:|     |.....:.|:.:....:..|||:|....|:.|.:::: .|.:|:.::
Mouse    97 RPGELTLLSVLPQLSQALGLEHQELQVVRAPGKEASGLVLLSSCPQTASRLQKFFIHSRRAQRPT 161

  Fly   459 EYICRVEGVFPDGIVECKE-----PIEV-----VSYKIGVCKVSAKG-----KDCTTTFQKLSQN 508
            ...|.|    .|||.|..|     |:::     |...:.|...|.|.     |...:.|..::..
Mouse   162 ATYCAV----TDGIPEPSEGTVCMPLKMEQMNDVDLAVPVMSPSRKDIQEGVKRTLSRFHVMATG 222

  Fly   509 GTTSVVLCKPLTGRMHQIRVHLQYLGYPILNDPLYNHEVFGPLKGRSGDIGGKS----------- 562
            ...::|..:|||...:|::||:.....|||.|..|        ..|.|.:.|:.
Mouse   223 RGCALVQLQPLTVFPNQLQVHMALQLCPILGDHTY--------AARVGTVLGQRFLWPAETTKPQ 279

  Fly   563 ----DEELIRDL 570
                ||.|:|.|
Mouse   280 RQVLDEALLRHL 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RluA-1	NP_723592.1	Auts2	21..>162	CDD:291981
RluA-1	NP_723592.1	PseudoU_synth_ScRIB2	363..547	CDD:211331	47/206 (23%)
Rpusd3	NP_001028376.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	25..53		4/8 (50%)
Rpusd3	NP_001028376.1	PseudoU_synth_RluCD_like	83..268	CDD:211346	49/198 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0564
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810