Protein Alignment LManII and AMS1

DIOPT Version :9

• Sequence 1: NP_609408.1
• Gene: LManII / 34437
• FlyBaseID: FBgn0027611
• Length: 1080
• Species: Drosophila melanogaster
• Sequence 2: NP_011359.1
• Gene: AMS1 / 852721
• SGDID: S000003124
• Length: 1083
• Species: Saccharomyces cerevisiae
• Alignment Length: 903
• Identity: 177/903 - (19%)
• Similarity: 310/903 - (34%)
• Gaps: 247/903 - (27%)

  Fly    46 MLNVHLVAHTHDDVGWLKTVDQYYYGSET--KIQKAGVQYIIDSVVEALLRDPEKRFIYVESAFF 108
            :.||:.:.:.|.|..||      :..:||  ||.::.     .|....:.|.||.:|: ...|..
Yeast   288 LTNVYGIGNCHIDTAWL------WPFAETRRKIVRSW-----SSQCTLMDRFPEYKFV-ASQAQQ 340

  Fly   109 FKWWKEQKPKVQEAVKM-LVEQGRLEFIGGAWSMNDEATTHYQSVIDQFSWGLRLLNDTFGECGR 172
            |||..|..|:....|.: .::|.:...:||.|..||......:|:..||.:|.|.....||.  :
Yeast   341 FKWLLEDHPEFFNKVLIPKIQQSQFFAVGGTWVENDTNIPSGESLARQFFFGQRFFLKHFGL--K 403

  Fly   173 PRVGWQIDPFGHSREMASMFAQMGFDGMFFGRLDYQDKDERLMTKNAEMIWHGSANLGEEADLFS 237
            .::.|..|.||:|.:|..:....|.|...         .::|...|.....|.:.|       ::
Yeast   404 SKIFWLPDTFGYSSQMPQLCRLSGIDKFL---------TQKLSWNNINSFPHSTFN-------WA 452

  Fly   238 GALYNNYQAPDGFCFDILCNDAPIIDGK----HSPDNNVKERIDTFLDFAKTQSQ-----YYRTN 293
            |                       |||.    |.|..|.......|.|..:|..|     ||.:.
Yeast   453 G-----------------------IDGSQLLTHMPPGNTYTADSHFGDVLRTAKQNKTPEYYGSG 494

  Fly   294 NIIVTM---GGDFTYQAAQVYYKNLDKLIRYGNERQANGSNINLLYSTPSCYLKSLHDAGITWPT 355
            .::...   ||..|.:.       |.|:.|..:....||:.|..|            ..|||...
Yeast   495 LMLYGKGDGGGGPTEEM-------LQKMRRIRSMNNRNGNVIPKL------------QVGITVDE 540

  Fly   356 KSDDFFPYASDPH--AYWTG--YF-------TSRPTLKRFERDGN---HFLQ-VCKQLSALAPKK 405
            ..||.....:..|  ..|:|  ||       ||:...|:..|...   |.|: :..:.|.|.|..
Yeast   541 FYDDILKRTNQGHDLPTWSGELYFEFHRGTYTSQAQTKKLMRLSEIKLHDLEWIAAKTSVLYPDS 605

  Fly   406 PEEFDPHLTFMRETLGIMQHHDAITGTEKEKV-ALDYAKRMSVAFRACGATTRNALNQLTVQSKD 469
            .:.....:..:.|.:.:.|.||.:.|:..|.| ..:....:....:.|.:.....:..|..|||.
Yeast   606 YKYPSKQINELWENVLLCQFHDVLPGSCIEMVYKYEAVPMLHNVVKECTSLIDKTVQFLQSQSKA 670

  Fly   470 NVKDTSAKYVFEFKTCALLNITSCPVSEANDRFALTLYNPLAHTVNEYVRIPVPYSNYRIIDN-- 532
            :        :.|.:|     :|.....:.::..:|.         ..|......|.:|.::.|
Yeast   671 D--------LVEMRT-----LTWSKPEKVSEECSLN---------GSYTSSVTGYDDYIVLANGK 713

  Fly   533 ------------KGVTLESQAVPIPQVLIDIKH-RNSTAKYEIVFLATNIPALGYRTY------- 577
                        ..:|.|:..|.    .:|.:| ||.....:  |:..:...||::.:
Yeast   714 LKVIICKKTGVITSITDETLGVE----YLDTEHGRNKLGANQ--FVIYDDKPLGWQAWDTELYSV 772

  Fly   578 ----YVEKLDSTE--GNTRSKA-----------------------------LPKRTSSVTV---- 603
                ||.|....:  .||:.|.                             |.|...|.||
Yeast   773 NQYKYVTKPKKVQVSCNTKEKCAVEVIFQISEKCKIKSVISLNATAVTDAKLSKVDISTTVENWD 837

  Fly   604 IGNSHIQLGFDT---NGFLSEVTADGLTRL-----VSQEFLFYEGAVGNNAEFLNRSSGAYIFRP 660
            ..|..:::.|..   |.|.|..|..|:|:.     .|.:...:|......|::...|.|..|.
Yeast   838 ARNKFLKVEFPVNIRNDFASYETQFGITKRPTHYNTSWDVAKFEVCHHKFADYSEYSKGVSIL-- 900

  Fly   661 NENKIHFAT--DQVEIEVYKGDLVHEVHQKFND-------------WISQVVRVYNKDSYAEFEW 710
            |:.|..|:|  :.:.:.:.:.....:.|.....             ..|..|::.::.:|. |::
Yeast   901 NDCKYGFSTHGNLMRLSLLRSPKAPDAHADMGTHEIKYAIYPHRGALSSDTVKLAHEFNYC-FKY 964

  Fly   711 LVGPIPIDDGIGKEVITRFNSD--IASDGIFRTDSNGREMIKRKINHRDTWS--VKINEAVAG-N 770
               .:|.|.|:..:.|...:.|  :....|.|.:.:........:|.||..|  |::.|::.| :
Yeast   965 ---KLPKDIGMNFDDIISISGDENVILSNIKRGEDDSAVKSNYSLNPRDEQSIVVRVYESLGGES 1026

  Fly   771 YYPITTKIDVEDDTARMAILTDRAQGGSSLKDGSLELMVHRRL--LKDDAFGVGEALN 826
            :..:.|.::::           |.:     |..:||:.|::.|  .:|::   ..|:|
Yeast  1027 FASLNTTLNLK-----------RIE-----KVDNLEMKVYKSLTATRDES---NHAIN 1065

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LManII	NP_609408.1	GH38N_AMII_LAM_like	47..323	CDD:212121	66/290 (23%)
		Alpha-mann_mid	370..445	CDD:214875	20/88 (23%)
		Glyco_hydro_38C	502..957	CDD:285047	73/416 (18%)
AMS1	NP_011359.1	AMS1	44..1083	CDD:223460	177/903 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344082
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3970
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960