Protein Alignment LManII and alpha-Man-IIb

DIOPT Version :9

• Sequence 1: NP_609408.1
• Gene: LManII / 34437
• FlyBaseID: FBgn0027611
• Length: 1080
• Species: Drosophila melanogaster
• Sequence 2: NP_001262614.1
• Gene: alpha-Man-IIb / 41913
• FlyBaseID: FBgn0026616
• Length: 1249
• Species: Drosophila melanogaster
• Alignment Length: 1220
• Identity: 290/1220 - (23%)
• Similarity: 468/1220 - (38%)
• Gaps: 339/1220 - (27%)

  Fly    47 LNVHLVAHTHDDVGWLKTVDQYYYGSETKIQKAGVQYIIDSVVEALLRDPEKRFIYVESAFFFKW 111
            |.:.:|.|:|:|.|||||...|:        ::..:.|::.:|..:....:..||:.|.:|...|
  Fly   168 LKIIVVPHSHNDPGWLKTFTNYF--------QSDSRQILNLLVTKMQEYTDMTFIWSEISFLQLW 224

  Fly   112 WKEQKPKVQEAVKMLVEQGRLEFIGGAWSMNDEATTHYQSVIDQF----SWGLRLLNDTFGECGR 172
            |.:..|..|.|:|.|::.||:|...|.|.|.|||..|...::||.    .|....||.|
  Fly   225 WDQAHPTKQRALKRLIDAGRIEITTGGWVMTDEANVHIYPMLDQLIEGHQWLKNNLNVT------ 283

  Fly   173 PRVGWQIDPFGHSREMASMFAQMGFDGMFFGRLDYQDKDERLMTKNAEMIWHGSANLGEEADLFS 237
            |:|||.||||||...:..:.:...|:|....|:.|..|......::.:.||.......::.|..:
  Fly   284 PKVGWSIDPFGHGSTVPYLLSGANFEGTIIQRIHYAWKQWFARQQSGDFIWKPYWRSRKDKDSEA 348

  Fly   238 GALYNNYQAPDGFCFDILCNDAPII----DGKHSP--------------DNNVKERIDTFLD-FA 283
            |:|..:....|.:.....|...|.|    |.:..|              |:|::.:....|: :|
  Fly   349 GSLLTHNMPFDIYSIKGSCGPHPFICLNFDFRKIPGEYTEYSVKAQFITDDNLESKAQLLLEQYA 413

  Fly   284 KTQSQYYRTNNIIVTMGGDFTY---QAAQVYYKNLDKLIRY--GNERQANGSNINLLYSTPSCYL 343
            :|.| .:..|..::.:|.||.|   :.....|:|..|||.:  .|.|..|.   ::.:.|||.|.
  Fly   414 RTAS-LFPHNVALIPVGDDFRYNKDREVDQQYQNYKKLIDHIMANRRLYNA---DIRFGTPSDYF 474

  Fly   344 KSL------HDAGITWPTKSDDFFPY----ASDPHAYWTGYFTSRPTLKRFERDGNHFLQVCKQL 398
            :::      |..|  :||...|||.|    :....|||:||||:||..|....:..|.|:..:.:
  Fly   475 EAIKERMKDHTPG--FPTFKGDFFVYSDIFSEGRPAYWSGYFTTRPFYKLLSSELEHQLRSAEIV 537

  Fly   399 SALAPKKPEE---------FDPHLTFM---RETLGIMQHHDAITGTEKEKVALDYAKRMSVAFRA 451
            ..||.....:         ::.:...:   |..||:.|||||||||.|..|..|||.|:.
  Fly   538 FTLAYNTARQAKRENAIKIYEKNYELIINARRNLGLFQHHDAITGTSKAAVMRDYAMRLF----- 597

  Fly   452 CGATTRNALN------QLTVQ--------------SKDNVKDTSAKYVFEFKTCALLNITSCPVS 496
              .:|:|.:.      :|.:|              .:||......|...:...    ...|.|..
  Fly   598 --ESTQNMVKMQESCLELLLQKGQPRHHGFLLSEFERDNFNKLPRKMPIQMAN----GDESTPTV 656

  Fly   497 EANDRFA-----------LTLYNPLAHTVNEYVRIPVPYSNYRIIDNKGVTLES-QAVPIPQVLI 549
            .|.:..|           ..|||.||....|.|.:.|.:.|.:|:::|||.|.. |..|:..:..
  Fly   657 PAGEGGAGGSSSSGSVGSFVLYNSLAQKRLEVVTLRVQHPNVKIVNDKGVELNHIQINPVWNITD 721

  Fly   550 DIKH-------------RNSTAKYEIVFLATNIPALGYRTYYVEK--------------LDSTEG 587
            ..:.             |.||.::|::|:| .:..|...||.|:.              .|.||.
  Fly   722 TYEQGLGTSVSGTVGRIRTSTRQFEVMFVA-ELEPLSLSTYRVQVDEVNFKRNIATIYCDDCTES 785

  Fly   588 NTRSKALPKRTSSVTV--------------IGNSHIQLGFD-TNGFLSEVTADG----LTRLVSQ 633
            ...|.:.|:...|...              :.|.|::|.|| .:|||..:|...    |.:.:..
  Fly   786 QPASVSPPEEIESSPTSVFEARGKPAGDIQLENPHMRLLFDEKSGFLKTITRKNQKKELLKPLQC 850

  Fly   634 EFLFYEGAVGNNAEFLNRSSGAYIFRPN------ENKIHFATDQVEIEVYKGDLVHEVHQKFNDW 692
            ...|   |...:|:|   .||||:|:.:      |.::......:.|.:..|.:..:|...:..:
  Fly   851 NIKF---AAYRSAQF---HSGAYLFKTDPEQSEAEKEVLEGYTDMRIIITSGPIASDVTVIYGPF 909

  Fly   693 ISQVVRVYNKDSYAEFEWLVGPIPIDDGIG---------KEVITRFNSDIASDG----------- 737
            ::..||::|..::     |...|.:::.|.         .|:..||.::|.:..
  Fly   910 LAHTVRIFNTRTH-----LDAAIYVENDIDFEPPPKNRETELFMRFVTNIDNIAQAPMQRDPLKE 969

  Fly   738 -----------IFRTDSNGREMIKRKINHRDTWSVKINE-AVAGNYYPITTKIDVEDDTARMAIL 790
                       :|.:|.||.:..:|         :|:.. .:.|||:|||:...::|...|:.:|
  Fly   970 PVDAATMPELPVFYSDQNGFQYHER---------IKVPAIGIEGNYFPITSGAFIQDSRLRLTLL 1025

  Fly   791 TDRAQGGSSLKDGSLELMVHRRLLKDDAFGVGEALNETEYGDGLIARGKHHLFFGKSTDREG--- 852
            |..|||.:|.:.|.||:|:.||.|.||..|:||.:.:        :|...|.|:....|..|
  Fly  1026 TTHAQGAASYEPGQLEVMLDRRTLYDDYRGMGEGVVD--------SRLTRHKFWLLVEDLPGGQH 1082

  Fly   853 --------VSLKGIERLTQLEKLLPTWKFFSNMEDYSADEWQTAFTNIFSGISLVLPK-----PV 904
                    |..:..::|....:..|...|.||:|       |.........:..:|||     .|
  Fly  1083 VTQPPSYKVLSQQAQQLANALRYPPNLYFVSNLE-------QPELAAALLPLVRLLPKGPLPCDV 1140

  Fly   905 HLLTLEPWHE---------NQLLVRFEHIMENGEDASYSQPVQFNVKNV--LSAFDVEGIRETTL 958
            ||.||....:         :.|||    :...|.|.|.|...:.:::.:  ||:   :|:
  Fly  1141 HLTTLRTLSDPELQLFPSASALLV----LHRQGFDCSVSAGRELSMEAICPLSS---KGL----- 1193

  Fly   959 DGNAWLDESRRLQFAPDPEEAAFNTYATFSQPAESVHLLSAEKPMLGVKYADEALPAGQLGAESN 1023
             ||..|.   ||                      |:|.:.|.. :.|.:.        :...||.
  Fly  1194 -GNVQLG---RL----------------------SLHTIEATS-LTGTEQ--------KSSRESY 1223

  Fly  1024 RIRRETETRQEKKDEGRSSKSTEGPYNSFKSDSSNQEYIIELSPMEIRTF 1073
            .||...|                                |.|.|||:|||
  Fly  1224 HIRSLAE--------------------------------ISLEPMELRTF 1241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LManII	NP_609408.1	GH38N_AMII_LAM_like	47..323	CDD:212121	82/303 (27%)
		Alpha-mann_mid	370..445	CDD:214875	30/86 (35%)
		Glyco_hydro_38C	502..957	CDD:285047	129/577 (22%)
alpha-Man-IIb	NP_001262614.1	PLN02701	148..1246	CDD:178304	290/1220 (24%)
		GH38N_AMII_GMII_SfManIII_like	167..514	CDD:212120	101/365 (28%)
		Alpha-mann_mid	508..596	CDD:286360	31/87 (36%)
		Glyco_hydro_38C	813..1241	CDD:285047	116/541 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450131
Domainoid	1	1.000	50	1.000	Domainoid score	I680
eggNOG	1	0.900	-	-		E1_KOG1959
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	49	1.000	Inparanoid score	I462
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.790