Protein Alignment LManII and LManIII

DIOPT Version :10

• Sequence 1: NP_609408.1
• Gene: LManII / 34437
• FlyBaseID: FBgn0027611
• Length: 1080
• Species: Drosophila melanogaster
• Sequence 2: NP_609250.2
• Gene: LManIII / 34203
• FlyBaseID: FBgn0032066
• Length: 1003
• Species: Drosophila melanogaster
• Alignment Length: 1079
• Identity: 484/1079 - (44%)
• Similarity: 657/1079 - (60%)
• Gaps: 143/1079 - (13%)

  Fly    36 YQSCHPTKPNMLNVHLVAHTHDDVGWLKTVDQYYYGSETKIQKAGVQYIIDSVVEALLRDPEKRF 100
            |:||..||.||:|:|||.|:|||:||||||||||||::..||.||||||.|:||..|.:|..:||
  Fly    26 YESCPETKSNMINIHLVPHSHDDLGWLKTVDQYYYGNKHNIQHAGVQYIFDTVVAELSKDSRRRF 90

  Fly   101 IYVESAFFFKWWKEQKPKVQEAVKMLVEQGRLEFIGGAWSMNDEATTHYQSVIDQFSWGLRLLND 165
            |.||:.||.|||::|....::.||.||.:|||||.||||||||||..:||||||||:.||:.|||
  Fly    91 IQVETGFFAKWWEDQSETKKKLVKTLVNEGRLEFTGGAWSMNDEAAVNYQSVIDQFAVGLKFLND 155

  Fly   166 TFGECGRPRVGWQIDPFGHSREMASMFAQMGFDGMFFGRLDYQDKDERLMTKNAEMIWHGSANLG 230
            .||.|||||||||||.||||||.|||||||.|||.||.|:|..||::|:.....||:|..|..|
  Fly   156 NFGVCGRPRVGWQIDAFGHSREQASMFAQMAFDGQFFARMDQNDKNKRVDNLGLEMVWDASETL- 219

  Fly   231 EEADLFSGALYNNYQAPDGFCFDILCNDAPIIDGKHSPDNNVKERIDTFLDFAKTQSQYYRTNNI 295
            ||.|.|:|.|||:|.||.|||||.||.|.|||||| |.|||||.|:|.||::|...:.|||:|:|
  Fly   220 EEMDFFTGMLYNHYSAPPGFCFDSLCQDDPIIDGK-SYDNNVKSRVDDFLNYASNLAGYYRSNHI 283

  Fly   296 IVTMGGDFTYQAAQVYYKNLDKLIRYGNERQANGSNINLLYSTPSCYLKSLHDAGITWPTKSDDF 360
            :|.||.||.|:.|.:.|||:||||:|.|||||:||..|:.|||..|||.|||.:..::|.|:.||
  Fly   284 MVPMGDDFQYENAYMNYKNMDKLIKYVNERQASGSKYNIFYSTAGCYLNSLHKSLQSFPNKTQDF 348

  Fly   361 FPYASDPHAYWTGYFTSRPTLKRFERDGNHFLQVCKQLSALAPKKPEEFDPHLTFMRETLGIMQH 425
            .|::.:..::|||:||||||.|||||||||.|||.||||.||....||....|.::|:.:.:|||
  Fly   349 LPHSHEAKSFWTGFFTSRPTQKRFERDGNHILQVAKQLSVLADLSGEEQHKDLDYLRQIMAVMQH 413

  Fly   426 HDAITGTEKEKVALDYAKRMSVAFRACGATTRNALNQLTVQSKDNVKDTSAKYVFEFKTCALLNI 490
            |||||||||::|:.||.:.:..|......|.|:||..||.|...           ||::|..|||
  Fly   414 HDAITGTEKQEVSNDYDRLLYDAILGGANTARDALRVLTNQPNG-----------EFQSCLKLNI 467

  Fly   491 TSCPVSEAN-DRFALTLYNPLAHTVNEYVRIPVPYSNYRIIDNKGVTLESQAVPIPQVLIDIKHR 554
            :.|..::.| |.|.:|||||||||..:|||:||...:|::.|.||..:.|:.||:|..::.::.|
  Fly   468 SECAFTKENADDFMVTLYNPLAHTSTQYVRVPVKEDSYQVTDEKGGLVASELVPVPWEVLSLEFR 532

  Fly   555 NSTAKYEIVFLAT-NIPALGYRTYYVEKLDSTEG-----NTRSK----------ALPKRTSSV-- 601
            |:..::|:||.|: |..|    ||:::|:|.|..     ||:::          .:|||...|
  Fly   533 NNDTQHELVFKASVNKIA----TYFIKKIDKTTEVDITVNTQTEQSVNEEESNVKVPKRFKKVHS 593

  Fly   602 ------------TVIGNSHIQLGFDTN-GFLSEVTADGLTRLVSQEFLFYEGAVGNNAEFLNRSS 653
                        |::.||.|:|..|.| |.|..|..:|::..:.|.|..|:.|          .|
  Fly   594 LKTDLETLDDQETIVQNSLIKLVIDNNTGRLKTVEMNGVSEDIDQTFGMYKTA----------RS 648

  Fly   654 GAYIFRPNENKIHFATDQVEIEVYKGDLVHEVHQKFNDWISQVVRVYNKDSYAEFEWLVGPIPID 718
            ..||||.:.: :....|..:..||.|:.|.||||..|:|||||:|:|...:..||||||||:|||
  Fly   649 CHYIFRQDAD-LELVEDAFDFTVYDGESVKEVHQHVNEWISQVIRIYEGVNRVEFEWLVGPVPID 712

  Fly   719 DGIGKEVITRFNSDIASDGIFRTDSNGREMIKRKINHRDTWSVKINE-AVAGNYYPITTKIDVED 782
            |.:|||::|.|.|.|:|.|:|.||||||||::|:.:.|:.:|..::| .|:|||||:|:::.::|
  Fly   713 DELGKEIVTIFKSGISSGGVFYTDSNGREMMRREKDKREDFSPDLSEQPVSGNYYPVTSRMALQD 777

  Fly   783 DTARMAILTDRAQGGSSLKDGSLELMVHRRLLKDDAFGVGEALNETEYGDGLIARGKHHLFFGKS 847
            .:.||.:|.||:|||:||:||.||:|:|||.:..|..|..||:||.::|.|||||||..|:....
  Fly   778 SSKRMVLLNDRSQGGASLEDGRLEMMLHRRHIFADGSGAAEAINEQQFGKGLIARGKLFLYLNAI 842

  Fly   848 TDREGVSLKGIERLTQLEKLLPTWKFFSNMEDYSADEWQTA--FTNIFSGISLVLPKPVHLLTLE 910
            .|....|    ||:.:.|..||.|||||...:..:|..:|.  |.:        ||:.|||||||
  Fly   843 EDGATAS----ERVAEKEIHLPFWKFFSKSNNIQSDVTKTLSDFND--------LPQSVHLLTLE 895

  Fly   911 PWHENQLLVRFEHIMENGEDASYSQPVQFNVKNVLSAFDVEG--IRETTLDGNAWLDESRRLQFA 973
            |:.::::|:|.|:.::..|    ...|.|:::.:..  |:.|  |||||||||..|.:.:||:|.
  Fly   896 PYSKDEILLRLENFLDQTE----GNVVSFSIRQIFD--DLGGLEIRETTLDGNLPLSDMKRLKFH 954

  Fly   974 PDPEEAAFNTYATFSQPAESV--HLLSAEKPMLGVKYADEALPAGQLGAESNRIRRETETRQEKK 1036
            .|.           |.|:.||  :..|..||:...|..|.:
  Fly   955 HDG-----------SGPSHSVPEYFTSLHKPLAADKTQDAS------------------------ 984

  Fly  1037 DEGRSSKSTEGPYNSFKSDSSNQEYIIELSPMEIRTFIV 1075
                                   |:.:.|.||:|||||:
  Fly   985 -----------------------EFSVTLKPMQIRTFII 1000

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LManII	NP_609408.1	PLN02701	47..823	CDD:178304	399/808 (49%)
		GH38N_AMII_LAM_like	47..323	CDD:212121	173/275 (63%)
LManIII	NP_609250.2	PLN02701	20..820	CDD:178304	407/821 (50%)
		GH38N_AMII_LAM_like	37..311	CDD:212121	173/275 (63%)