DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment LManI and AT5G66150

DIOPT Version :9

Sequence 1:	NP_001260350.1	Gene:	LManI / 34436	FlyBaseID:	FBgn0032253	Length:	950	Species:	Drosophila melanogaster
Sequence 2:	NP_201416.1	Gene:	AT5G66150 / 836747	AraportID:	AT5G66150	Length:	1047	Species:	Arabidopsis thaliana

Alignment Length:	1042	Identity:	361/1042 - (34%)
Similarity:	539/1042 - (51%)	Gaps:	153/1042 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 INVHLVPHSHDDVGWLKTVDQYYYGSQNKIQHAGVQYILDTVVEELLKDSSRRFIQVETFFFAKW 66
            :||||||||||||||||||||||.||.|:||:|.|:.:||:||:.||:|.:|:|:..|..||.:|
plant    47 LNVHLVPHSHDDVGWLKTVDQYYVGSNNRIQNACVRNVLDSVVDSLLRDPNRKFVFAEMAFFTRW 111

  Fly    67 YSEQTETVQRAVKKLVAQGRLEFAGGAWSMNDEATVHYQSVVDQFNLGLRYLKDTFGDCGRPTVG 131
            :.||:...|..|::||..|:|||..|.|:||||||.||..::||...|.|::|..|..  .|...
plant   112 WEEQSPERQEQVRRLVKSGQLEFVNGGWAMNDEATCHYIDMIDQTTKGHRFIKQQFNT--TPRAA 174

  Fly   132 WQIDPFGHSREMASIF-AQMAFNGEFFARMDYVDKKQRMLDLEMEMIWQSSESL-KNSNIFTGML 194
            |||||||||...|.:. |::..:...|||:||.|:::|..:..:|:||:.|::| .:|.|||.:.
plant   175 WQIDPFGHSSVQAYLLGAELGLDSVHFARIDYQDREKRKAEKSLEVIWRGSKTLDSSSQIFTNIF 239

  Fly   195 YNHYSAPPGFCFDINCEDAPIIDGESYDN-NVDARVSEFIDYVKNMSKSY----RSTHIMVPMGD 254
            :.||..|.||.:::..:..|:.|...:|. |:...|::|:    |.|..|    |..|:|..|||
plant   240 FVHYGPPTGFHYEVTDDYVPLQDNPRFDGYNIKEAVNDFV----NASLVYANVSRGNHVMWTMGD 300

  Fly   255 DFQYEDAAVNFKNMDKLIKYVNDRQSTGSQVNVFYSTPSCYLYELHQLKQTWPNKTEDFFPYSSD 319
            ||||:.|...|:.||:||.|||    ...:||..|||||.|:...:....|||.||.|||||:..
plant   301 DFQYQFAESWFRQMDRLIHYVN----KDGRVNALYSTPSLYVDAKNVANVTWPLKTHDFFPYADR 361

  Fly   320 SHSYWTGYFTSRPTQKRFHRDGNHFFQTVKQLSVLA--NLSG-TQYSEDLDNLSQAMGIMQHHDA 381
            :::||||||||||..||:.|..:.::...:||..|.  |..| ..||     |..|:||.|||||
plant   362 AYAYWTGYFTSRPALKRYVRALSGYYMAARQLEFLVGKNSGGPNTYS-----LGDALGIAQHHDA 421

  Fly   382 VTGTEKQAVASDYDRLLFKAIVGAENSARDALRSLTNLTS---------GEFESCLELNISVCAF 437
            ||||.||.|.:||.:.|......||.....||..|.|...         ...:.|..:|||.|..
plant   422 VTGTAKQHVTNDYMKRLALGASEAEAVVNSALACLMNKAPKGGCTKPAIAFSQQCSLMNISYCPS 486

  Fly   438 TQDT---ANNVIVTLVNPLAHSSTQYVRVPAKNENYIVTDEKGREVFSEVVPV------------ 487
            |::|   ..::|:...|.|..:.|:.:|:|..:....|.|..|..:.::.:|:
plant   487 TEETLPGQKSLILVAYNSLGWNRTEIIRIPVNDAGLSVEDSSGNTLDAQYIPMDNVTSNLRSFYT 551

  Fly   488 -PWQVLALEHRPNDTQHELVFEASVDKIA--NFLI--------------RVLPSPKNIAEDQVQF 535
             .:..::...||   ::.|||:|.|..:.  .|.|              .|:.||.|
plant   552 KAYLGISSLQRP---KYWLVFKAKVPPLGWNTFFISKASAQGSNNHKHSSVMLSPMN-------- 605

  Fly   536 PVERSQDELTVETSLVKLTFDTTTGGLKTV--KMNGFTENIQQTFGIYKGYRGNNGESKN-RSSG 597
                  :...:....:|:.|.:.:|.|:.:  ...|....:.|.   |..|..|.|::|: :.||
plant   606 ------NTTEIGPGNLKMVFSSDSGRLERMYNSRTGADIKVDQN---YFWYASNVGDAKDPQVSG 661

  Fly   598 AYVFRPYGDIE---------------IVNNKVE--LSFYNGTKVKEVHQHVNEWISQVIRIYEDV 645
            ||:|||.|.:.               |.|..|:  |....|..:.||||..:.|::||:|:|::.
plant   662 AYIFRPNGSLAYPVSSSKICTVTSAFIGNGNVQSKLQIVRGPLIDEVHQQFSPWVAQVVRLYKEK 726

  Fly   646 NRVEFEWLVGPIPTDDD--VGKEIITRFSSNISSKGKFYTDSNGREILERERNQREHFTPDMSEA 708
            ...|||:.:|||.....  .|||||||..:::::..:||||||||:.|:|.|:.|..:..:::|.
plant   727 EHAEFEFTIGPISVGKGHLTGKEIITRMVTDMTTAKEFYTDSNGRDFLKRVRDNRTDWHLEVNEP 791

  Fly   709 ISGNYYPVTGQISLQDDEKRITLLNDRAQGGTSLKDGELELMLHRRLLNDDAFGVGEALNET--- 770
            |:|||||:...:.::|::..:::|.|||.||.|:||||:|||||||...||:.||.|:|.||
plant   792 IAGNYYPLNLGMYIKDEKAELSVLVDRATGGASIKDGEIELMLHRRTSMDDSRGVEESLVETVCV 856

  Fly   771 -QYGTGLIARGKIYLILDAV-DG------------KPNQRLLQHQLDQHFWKFFSKSNGVASVNR 821
             ....||..||..|:.::.| :|            .|......|: ::..||..:...|.|
plant   857 NDTCAGLTIRGNYYVSINKVGEGGRWRRETGQEIYSPLLMAFAHE-NKEKWKASNTVKGYA---- 916

  Fly   822 NMIPDFFGIPESVELLSLEPYSKDQILIRLENFNTEG------NVVSFNIYPLFESLDGYQIWET 880
              :...:.:|:::.|::||......:|:||.:....|      .:....:..||......::.|.
plant   917 --MDHLYTLPQNIALITLEELDLGNVLLRLAHLYEAGEDSDYSKIAKVELKKLFSGKMIKEVTEM 979

  Fly   881 TLDGNMLLEDVK---RFKFAQDGTGSIPSSVEYYHAPHNPLTANSTMNASGFVVTLVPMQIRTFI 942
            :|..|.  |.||   :.|:..:|....|||         || ....::.|..||.|.||:||||:
plant   980 SLSANQ--EKVKMKEKMKWKVEGEAEQPSS---------PL-RGGPVDKSTLVVELGPMEIRTFV 1032

  Fly   943 IQ 944
            :|
plant  1033 VQ 1034

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LManI	NP_001260350.1	GH38N_AMII_LAM_like	2..276	CDD:212121	127/280 (45%)
		Alpha-mann_mid	323..398	CDD:286360	38/77 (49%)
		Glyco_hydro_38C	536..941	CDD:285047	136/452 (30%)
AT5G66150	NP_201416.1	GH38N_AMII_LAM_like	47..323	CDD:212121	129/285 (45%)
		Alpha-mann_mid	365..438	CDD:214875	38/77 (49%)
		Glyco_hydro_38C	498..1031	CDD:285047	159/571 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	310	1.000	Domainoid score	I311
eggNOG	1	0.900	-	-		E1_KOG1959
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	649	1.000	Inparanoid score	I170
OMA	1	1.010	-	-		QHG55625
OrthoDB	1	1.010	-	-		D201312at2759
OrthoFinder	1	1.000	-	-		FOG0001724
OrthoInspector	1	1.000	-	-		mtm1010
orthoMCL	1	0.900	-	-		OOG6_101099
Panther	1	1.100	-	-	O	PTHR11607
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1279
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840