Protein Alignment loh and adamtsl7

DIOPT Version :10

• Sequence 1: NP_609406.2
• Gene: loh / 34435
• FlyBaseID: FBgn0032252
• Length: 880
• Species: Drosophila melanogaster
• Sequence 2: XP_017211532.3
• Gene: adamtsl7 / 556634
• ZFINID: ZDB-GENE-070816-2
• Length: 643
• Species: Danio rerio
• Alignment Length: 615
• Identity: 157/615 - (25%)
• Similarity: 248/615 - (40%)
• Gaps: 89/615 - (14%)

  Fly   321 CKAVQASGEIDGLYAHSGSVSC---GGLLCRPVTGIFTRNPLPEHAYIHVTTLPVGASNISITEL 382
            |:..|.  ::.|:.|..|| ||   .|.:...|..:         .|..:..:|.||..|.|.|.
Zfish    48 CEGFQV--DVCGVCAGDGS-SCELFNGTIFLSVLSV---------RYHKILDIPSGALRIKIQET 100

  Fly   383 KNSINLLVLRTSNELAIFNGENTVSESGSYEAVGAVFDYHRIDGAEDSNGVTEWITSIGPIRDSL 447
            ..:.|.|.|..:...::.||:..:...|.:.|.|..|.|.|.:......|  |.||:.||....|
Zfish   101 HKTRNYLALSMATGESVINGDWVIDRPGQFYAAGTQFTYKRPNEIRSRAG--ESITAPGPTNQEL 163

  Fly   448 QLMVFTKSANNTGVKYEYMLPIVSESEENEMSLES------SDGLLRSGMEDTSSSSSSRAGRKR 506
            .|.|..:.. :..|.|||:||..:.:..:..|..|      |.|:..........:|.|.....:
Zfish   164 NLFVIYQQP-DAAVYYEYILPKHTNTHSDAYSYSSVLPLVESHGIFPDSENSVGENSLSSFHPNQ 227

  Fly   507 I------------FNWKVIGFSSCTKSCGGGTQTPIIRCIRKNPLRYYSQRRCTHSVKPVLNENL 559
            :            ::|..:..:.|:.:||.|.:..:..|:.:.......:..|:....|  ...:
Zfish   228 VPSDSVTLEPVPLYSWMAMATTPCSTTCGTGNRQVLFGCVERATQTTVLEDLCSSITHP--GPQV 290

  Fly   560 LHCNTQPCPAYWRFDDWGECRCSSSGGLRRREVSCVQ---ELASGLVIHVDKAACMEDQPP---- 617
            ..|.:|||||:|...:|.||..:...|.:.|:|.|.|   :..|..|: |..:.|.:.:.|
Zfish   291 EECQSQPCPAFWDVGEWSECSKTCGPGFQYRQVICRQTQGQHGSSTVV-VANSMCDDTEMPDTTS 354

  Fly   618 --MQKQC----------ECP-----KNRRRNLSRYRLSGPSESSSNSSQVKR----SKIDGSDAT 661
              ..|.|          ||.     ..|.|.:......|...|....:...|    ...|.....
Zfish   355 VCQLKICSEWQIRSEWTECSVPCGVGQRSREVVCVDNLGDIVSDEECNMALRPQDLQNCDKGVCA 419

  Fly   662 AIWLVSDWNQYCSVTCGSGVEYRTVFCDRSKAGE---QRCDPSTTPESRRPCE-KPACELGDWFT 722
            :.|..|.|::.||..|..|...|:|.|..|::..   ..||....|:....|: .|..:..:|:|
Zfish   420 SSWFYSLWSERCSADCAEGSRSRSVVCLMSQSNSLPLDDCDDEDKPDELMQCDLGPCTQRLEWYT 484

  Fly   723 GPWSSCNGDCFDLTRTREVLCIRSQ----LITEHSECTPELKPQSVEKCSHEEVEYCAARWHYSD 783
            |||..|:.:|.:.|::|.|:|:...    .:|....|:...:|.:.:.|   .::.|||:|..::
Zfish   485 GPWGQCSSECGNGTQSRGVVCVVQNGGHLEVTSDDLCSHLPRPPTAQSC---YLKSCAAQWFMTE 546

  Fly   784 WSECTKPCGGGTQRRSVRCLEYDIKMNALRESTHCRYTNREPI-YRNCNVQACAEVPKTEVTPVC 847
            ||.|::.|.||.:.|.||||..|:      .|:|......||. ...||...|.    .::...|
Zfish   547 WSSCSRSCEGGFRVREVRCLRDDL------TSSHDCDPALEPAKQEKCNTHICT----LQIDESC 601

  Fly   848 ADKFSNCQWASQAKLCSYDYYRDNCCFSCT 877
            .|.:.||....||:||.|.|||..||.||:
Zfish   602 RDMYYNCVVVVQARLCVYSYYRTTCCASCS 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
loh	NP_609406.2	TSP1	182..238	CDD:214559
		ADAMTS_spacer1	349..468	CDD:461796	32/118 (27%)
		TSP1_ADAMTS	510..567	CDD:465950	10/56 (18%)
		TSP1_ADAMTS	664..715	CDD:465950	16/54 (30%)
		TSP1_ADAMTS	720..768	CDD:465950	14/51 (27%)
		TSP1_ADAMTS	779..835	CDD:465950	19/56 (34%)
		PLAC	847..877	CDD:462560	15/29 (52%)
adamtsl7	XP_017211532.3	None