DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment loh and mig-17

DIOPT Version :9

Sequence 1:NP_609406.2 Gene:loh / 34435 FlyBaseID:FBgn0032252 Length:880 Species:Drosophila melanogaster
Sequence 2:NP_505901.2 Gene:mig-17 / 179575 WormBaseID:WBGene00003248 Length:509 Species:Caenorhabditis elegans


Alignment Length:349 Identity:58/349 - (16%)
Similarity:100/349 - (28%) Gaps:152/349 - (43%)


- Green bases have known domain annotations that are detailed below.


  Fly    18 HDSSFVQADLTTKERIKKHQDWLR--------EHRKPKTK-KKISIN--------SY-------- 57
            ::|:.:...:.:|:.|.|...||:        ||....|| ..||||        :|        
 Worm   218 NNSTEMTLKIDSKKAIDKFTIWLKEQTGLPRHEHAVLITKFDLISINGNSATQGMAYVGNICENG 282

  Fly    58 -------------------YELANLWHTRKDLSSPKQKPNNKEEYLENETTSKISNKSDEKVLKS 103
                               :|:.:......|.:....:.::.:.||   ....:|..:|.:..  
 Worm   283 DSSSVVEDIGAGLTSLIMAHEIGHSLGALHDGAYETAECDSNDNYL---MAVAVSGSADRQSF-- 342

  Fly   104 STIISLNATNPSTSTFKSVLETTTLPSVTTKDLFESGNVATTRQTPKVEEVFSSPNPPQEATSST 168
                 ||:...|..:..|::|....|         :.|.....:|.|.::|              
 Worm   343 -----LNSRRMSNCSINSIIENLKEP---------TANCVKKWKTKKGKDV-------------- 379

  Fly   169 SKKAKKKVYPYPRWDKWSDWSSCSRSCGGGVKYQVRKCINRNLLTNNQLTSNACVGYFKRYQLCN 233
            |:|...|        |..:....:|.|..........|::              :|||....:|.
 Worm   380 SQKDFIK--------KPGELVKITRQCQVAFGPTFIPCLH--------------IGYFHEQSICE 422

  Fly   234 DVPCDEQSPDFRASQCSAYNDKEFHGHRYRWEPYVKDDAECE-LNCMPFGMKSFATLNESVIDGT 297
            .:.|.:...|                             ||: ||..|            ..|||
 Worm   423 RIWCSDGESD-----------------------------ECQTLNYFP------------AFDGT 446

  Fly   298 PCGHPAEYFRSQFWERAVCVDGAC 321
            .||:       ..|    |::|:|
 Worm   447 ECGY-------NMW----CLEGSC 459

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
lohNP_609406.2 TSP1 182..238 CDD:214559 8/55 (15%)
ADAM_spacer1 348..468 CDD:283607
TSP1 667..716 CDD:214559
TSP1 779..835 CDD:214559
PLAC 847..877 CDD:285849
mig-17NP_505901.2 ZnMc_ADAM_like 162..361 CDD:239795 26/152 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C160156139
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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