Protein Alignment loh and AdamTS-B

DIOPT Version :10

• Sequence 1: NP_609406.2
• Gene: loh / 34435
• FlyBaseID: FBgn0032252
• Length: 880
• Species: Drosophila melanogaster
• Sequence 2: XP_061500773.1
• Gene: AdamTS-B / 1282050
• VectorBaseID: AGAMI1_010468
• Length: 1042
• Species: Anopheles gambiae
• Alignment Length: 583
• Identity: 146/583 - (25%)
• Similarity: 213/583 - (36%)
• Gaps: 135/583 - (23%)

  Fly   117 STFKSVLETTTLPSVTTKDLFESGNVATTRQTPKVEEVFSSP--NPPQEATSSTSKKAKKKVYPY 179
            ||.:.:...:.|..:.|:.....|.|.||...|      ::|  |..:.......|....:..|.
Mosquito   533 STDEDMTVCSKLDEICTQLWCLVGEVCTTMLRP------AAPGTNCGRRMWCQNQKCVDVEELPA 591

  Fly   180 P---RWDKWSDWSSCSRSCGGGVKYQVRKCINRNLLTNNQLTSNACVGYFKRYQLCNDVPCDEQS 241
            |   .|..||.||.||||||.|:..|.|:|.:.:.......    |:|...||:.|:...|...:
Mosquito   592 PVDGGWGDWSPWSECSRSCGVGIAKQTRECDHPSPAHGGMF----CIGERARYKTCHVQACPLGT 652

  Fly   242 PDFRASQCSAYNDKEFHGHRYRWEPYVKDDAECELNC--------MPFGMKSFATLNESVIDGTP 298
            |.|||.||||:::....|.:|.|.||...:..|||.|        :|||        ::..|||.
Mosquito   653 PSFRAEQCSAHDNDTIKGEKYTWLPYFDKNEPCELYCSNTEDTMIVPFG--------DTAADGTF 709

  Fly   299 CGHPAEYFRSQFWERAVCVDGACKAVQASGEIDGLYAHSGSVSCGGL--LCRPVTGIFTRNPLPE 361
            |         ......:|:.|.|:.|.....:|..........|||.  .|....|...:.....
Mosquito   710 C---------NLGTNDMCIGGICRKVGCDWVVDSNTTEDRCGVCGGTGDTCFVKKGEINKKINTT 765

  Fly   362 HAYIHVTTLPVGASNISITELKNSINLL-VLRTSNELAIFNGENTVSESGSYEAVGAVFDYHRID 425
            .....|..:|.||.|:.|.|:..|.|.: |.|::......|..:.:...|.||...::..|.|
Mosquito   766 DGVHDVLMIPAGARNVLIEEILPSKNFIGVGRSTGNECYLNCNHFIQLPGEYEVASSLCLYER-- 828

  Fly   426 GAEDSNGVTEWITSIGPIRDSLQLMVFTKSANN-TGVKYEYMLPIVSESEENEMSLESSDGLLRS 489
                 ....|.:...|||.:.:.:.:..|..|| .|::|||.||  |.:.:|:.:
Mosquito   829 -----ENEQERLKIPGPIMEDVNVFIVIKKKNNQAGIRYEYTLP--SHNGKNQSA---------- 876

  Fly   490 GMEDTSSSSSSRAGRKRIFNWKVIGFSSCTKSCGGGTQTPIIRCIRKNPLRYYSQRRCTHSVKPV 554
                              :.||:..:|.|:.:||||.|              :.:..|.|..|.|
Mosquito   877 ------------------YYWKLTDWSVCSATCGGGKQ--------------FRESICYHRGKGV 909

  Fly   555 LNEN--LLH------------CNTQPCPAYWRFDDWGEC--RCSSSG---GLRRREVSCVQELAS 600
            ..|.  |.|            ||..|||..|....|..|  .|....   .:|||.:.||...::
Mosquito   910 AKEEQCLRHAFGKRHEPIARDCNDDPCPFNWWVGPWQLCPMTCRKPHKPVPIRRRSILCVDSNSN 974

  Fly   601 GLV-IHV-------DKAACMEDQPPMQKQCECPKNRRRNLSRYRLS-------GPSESSSNSS 648
            ... .|.       ||..|.|:.|      .|.:|:|......|..       |||:..|.|:
Mosquito   975 ARPDTHCNNKPRPHDKEPCGEELP------VCQENQRSGQETERPDTIPFEEFGPSDLPSPST 1031

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
loh	NP_609406.2	TSP1	182..238	CDD:214559	20/55 (36%)
		ADAMTS_spacer1	349..468	CDD:461796	29/120 (24%)
		TSP1_ADAMTS	510..567	CDD:465950	18/70 (26%)
		TSP1_ADAMTS	664..715	CDD:465950
		TSP1_ADAMTS	720..768	CDD:465950
		TSP1_ADAMTS	779..835	CDD:465950
		PLAC	847..877	CDD:462560
AdamTS-B	XP_061500773.1	None