Protein Alignment STUB1 and SGTA

DIOPT Version :10

• Sequence 1: NP_477441.1
• Gene: STUB1 / 34433
• FlyBaseID: FBgn0027052
• Length: 289
• Species: Drosophila melanogaster
• Sequence 2: NP_003012.1
• Gene: SGTA / 6449
• HGNCID: 10819
• Length: 313
• Species: Homo sapiens
• Alignment Length: 234
• Identity: 55/234 - (23%)
• Similarity: 93/234 - (39%)
• Gaps: 56/234 - (23%)

  Fly    16 QLKEQGNCLFAARKYDDAINCYSKAIIKNPTNATYFTNRALCNLKLKRWELCCQDSRRALDIDGN 80
            :||.:||.......::.|::.|.|||..||.||.||.|||....||..:....||..||:.||..
Human    93 RLKTEGNEQMKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKLGNYAGAVQDCERAICIDPA 157

  Fly    81 LLKGHFFLGQGLMEIDNFDEAIKHLQRAYDLSKEQ---KQNFGDDITLQLRLARKK--------- 133
            ..|.:..:|..|..::...||:.:.::|.:|..:.   |.|        |::|..|
Human   158 YSKAYGRMGLALSSLNKHVEAVAYYKKALELDPDNETYKSN--------LKIAELKLREAPSPTG 214

  Fly   134 -------------------RWNVMEEKRIQQEIELQSYLNGLIKG-----------DMESRLANL 168
                               ..|:|...:|||      .::|:|.|           ..::.||:|
Human   215 GVGSFDIAGLLNNPGFMSMASNLMNNPQIQQ------LMSGMISGGNNPLGTPGTSPSQNDLASL 273

  Fly   169 KLNGNVHDEQLKDKQQEIEQECDDHIKELNNIFSKVDER 207
            ...|....:|::.:..|:.::....|:......|..|::
Human   274 IQAGQQFAQQMQQQNPELIEQLRSQIRSRTPSASNDDQQ 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
STUB1	NP_477441.1	TPR repeat	17..42	CDD:276809	8/24 (33%)
		TPR	21..>111	CDD:440225	30/89 (34%)
		TPR repeat	47..77	CDD:276809	13/29 (45%)
		TPR repeat	82..110	CDD:276809	6/27 (22%)
		CHIP_TPR_N	130..211	CDD:436460	19/117 (16%)
		RING-Ubox_CHIP	213..283	CDD:438316
SGTA	NP_003012.1	SGTA_dimer	5..64	CDD:465168
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	66..100		3/6 (50%)
		Spy	85..>199	CDD:443119	35/113 (31%)
		TPR 1	91..124		11/30 (37%)
		TPR repeat	91..119	CDD:276809	8/25 (32%)
		TPR repeat	124..154	CDD:276809	13/29 (45%)
		TPR 2	125..158		14/32 (44%)
		TPR 3	159..192		7/32 (22%)
		TPR repeat	159..187	CDD:276809	6/27 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	250..269		2/18 (11%)