DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment STUB1 and unc-45

DIOPT Version :9

Sequence 1:	NP_477441.1	Gene:	STUB1 / 34433	FlyBaseID:	FBgn0027052	Length:	289	Species:	Drosophila melanogaster
Sequence 2:	NP_001303425.1	Gene:	unc-45 / 44910	FlyBaseID:	FBgn0010812	Length:	947	Species:	Drosophila melanogaster

Alignment Length:	128	Identity:	36/128 - (28%)
Similarity:	59/128 - (46%)	Gaps:	13/128 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 KEQGNCLFAARKYDDAINCYSKAI---IKNPTNATYFTNRALCNLKLKRWELCCQDSRRALDIDG 79
            |::||..|.|.::::|:..|.|||   .|:...|.::.|||...|||.::|...:|...:|....
  Fly    17 KDKGNEAFKASRWEEAVEHYGKAIKAGSKHKELAVFYKNRAAAYLKLGKYENAVEDCTESLKAAP 81

  Fly    80 NLLKGHFFLGQGLMEIDNFDEAIKHLQRAYDLSKEQKQNFGDDITLQLRLARKKRWNVMEEKR 142
            ...|..|...|....::.|:||.|.....:......|       |:|..|   :|.:|:.|:|
  Fly    82 GDPKALFRRAQAYEALEKFEEAYKDATALFKADPGNK-------TVQPML---QRLHVVVEER 134

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
STUB1	NP_477441.1	TPR_11	17..78	CDD:290150	21/62 (34%)
		TPR	17..47	CDD:197478	11/31 (35%)
		TPR repeat	17..42	CDD:276809	10/26 (38%)
		TPR repeat	47..77	CDD:276809	10/29 (34%)
		TPR repeat	82..110	CDD:276809	7/27 (26%)
		U-box	213..285	CDD:252675
unc-45	NP_001303425.1	TPR_11	12..81	CDD:290150	21/63 (33%)
		TPR repeat	16..41	CDD:276809	9/23 (39%)
		TPR repeat	46..79	CDD:276809	10/32 (31%)
		TPR_11	50..115	CDD:290150	17/64 (27%)
		TPR	50..83	CDD:197478	10/32 (31%)
		UNC45-central	351..494	CDD:288539
		ARM	668..788	CDD:237987
		armadillo repeat	753..789	CDD:293788
		armadillo repeat	795..826	CDD:293788
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462447
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840