DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment STUB1 and HIP

DIOPT Version :9

Sequence 1:	NP_477441.1	Gene:	STUB1 / 34433	FlyBaseID:	FBgn0027052	Length:	289	Species:	Drosophila melanogaster
Sequence 2:	NP_570074.3	Gene:	HIP / 318211	FlyBaseID:	FBgn0260484	Length:	377	Species:	Drosophila melanogaster

Alignment Length:	174	Identity:	47/174 - (27%)
Similarity:	82/174 - (47%)	Gaps:	31/174 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 QLKEQGNCLFAARKYDDAINCYSKAIIKNPTNATYFTNRALCNLKLKRWELCCQDSRRALDIDGN 80
            :|:.|....:..:|:|:||..|:|||..:|.||.:...|....||||:...|.:|...||:::.:
  Fly   128 ELRAQAASAYGQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSD 192

  Fly    81 LLKGHFFLGQGLMEIDNFDEAIKHLQRAYDLSKEQKQNFGDDITLQLR----LARKKRWNVMEEK 141
            |..|:.|.|:....:.:|:.|      |:||.:..|.:|.::....|:    .|:|     :|:.
  Fly   193 LAAGYKFRGRARRLLGDFELA------AHDLRQACKLDFDEETDEWLKEVTPNAKK-----IEQH 246

  Fly   142 RIQQEIELQSYLNGLIKGDMESRLANLKLNGNVHDEQLKDKQQE 185
            |::|                |.|.|..|:.....|::...|:||
  Fly   247 RLKQ----------------ERRQAERKIKERQRDQRRARKEQE 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
STUB1	NP_477441.1	TPR_11	17..78	CDD:290150	22/60 (37%)
		TPR	17..47	CDD:197478	11/29 (38%)
		TPR repeat	17..42	CDD:276809	9/24 (38%)
		TPR repeat	47..77	CDD:276809	11/29 (38%)
		TPR repeat	82..110	CDD:276809	6/27 (22%)
		U-box	213..285	CDD:252675
HIP	NP_570074.3	Hip_N	10..47	CDD:271228
		TPR_11	125..190	CDD:290150	22/61 (36%)
		TPR_2	126..159	CDD:285020	11/30 (37%)
		TPR repeat	126..154	CDD:276809	9/25 (36%)
		TPR repeat	159..189	CDD:276809	11/29 (38%)
		TPR repeat	194..222	CDD:276809	8/33 (24%)
		STI1	299..336	CDD:128966
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462445
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840