Protein Alignment STUB1 and Ttc12

DIOPT Version :10

• Sequence 1: NP_477441.1
• Gene: STUB1 / 34433
• FlyBaseID: FBgn0027052
• Length: 289
• Species: Drosophila melanogaster
• Sequence 2: XP_006243066.1
• Gene: Ttc12 / 300696
• RGDID: 1303264
• Length: 723
• Species: Rattus norvegicus
• Alignment Length: 292
• Identity: 66/292 - (22%)
• Similarity: 106/292 - (36%)
• Gaps: 80/292 - (27%)

  Fly    17 LKEQGNCLFAARKYDDAINCYSKAIIKNPTNATYFTNRALCNLKLKRWELCCQDSRRALDIDGNL 81
            |||:||..|....|:.||..||:.:.|.......:||||...:||..::....|...||..|.|.
  Rat   127 LKEKGNEAFVKGDYETAIFFYSEGLGKLKDMKVLYTNRAQAYIKLGDYQKALVDCDWALKCDENC 191

  Fly    82 LKGHFFLGQGLMEIDNFDEAIKHLQRAYDLSKEQKQNFGDDITLQLRLARKKRWN--VMEEKRIQ 144
            .|.:|.:|:..:.:.|           |..|||..|..| :|..:|:...|:..|  .:.||...
  Rat   192 TKAYFHMGKAHLALKN-----------YSKSKECYQKIG-EINPKLKAQVKEHLNQVTLREKADL 244

  Fly   145 QEIELQSYLNGLIKGDMESR--LANLKLNGN---------------------------------V 174
            ||.:.:..|:......|.:|  |..|...|.                                 :
  Rat   245 QEKKARESLDSGKNTAMTTRNLLETLSKPGQTPLFYAGGIEILTEMMTDCTERTLFRTYGGFSII 309

  Fly   175 HDEQL---------KDKQQEI---------EQECDDHIKELNNIFSKVDERRKKREVPDFLCGKI 221
            :|.::         ||..:||         ::.|.|:.:....:.|..|   ..:.:|.|:..:|
  Rat   310 NDHEVIKRCLFLAGKDAVEEIVCVSVLKLWQEVCIDNEENQRLLLSHPD---MAKLLPSFMDSRI 371

  Fly   222 ------SFEILTDPVITPSGITYERKDIEEHL 247
                  |..:|.....|.:|    |..:.:||
  Rat   372 LVIQQQSLALLLQLTQTDNG----RNQVIKHL 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
STUB1	NP_477441.1	TPR repeat	17..42	CDD:276809	11/24 (46%)
		TPR	21..>111	CDD:440225	25/89 (28%)
		TPR repeat	47..77	CDD:276809	9/29 (31%)
		TPR repeat	82..110	CDD:276809	4/27 (15%)
		CHIP_TPR_N	130..211	CDD:436460	21/135 (16%)
		RING-Ubox_CHIP	213..283	CDD:438316	10/41 (24%)
Ttc12	XP_006243066.1	TPR	123..>224	CDD:440225	34/108 (31%)
		TPR repeat	124..152	CDD:276809	11/24 (46%)
		TPR repeat	157..187	CDD:276809	9/29 (31%)
		TPR repeat	192..217	CDD:276809	8/35 (23%)