Protein Alignment holn1 and LIN1

DIOPT Version :10

• Sequence 1: NP_609404.2
• Gene: holn1 / 34432
• FlyBaseID: FBgn0032250
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_012026.1
• Gene: LIN1 / 856561
• SGDID: S000001199
• Length: 340
• Species: Saccharomyces cerevisiae
• Alignment Length: 312
• Identity: 81/312 - (25%)
• Similarity: 140/312 - (44%)
• Gaps: 63/312 - (20%)

  Fly     3 SKRKHQASQKVKEESFKK---HTLDSDEE--------DSDDYEREYLNDSDIE-GGEEGVAKVED 55
            |.....:.:::.|:|::|   |..|..:.        |..::::|.|.|.|.: |..|  :|||.
Yeast    57 STDNENSGKEMDEKSYEKNEDHVEDHRKRKKSKIQLLDIAEFKKENLADLDYQIGNSE--SKVEK 119

  Fly    56 DVKVTPFNMKEELEEGHFDKDGHYHWNKETEAKDNWLDNIDWVK--IGTQK-NAFDPAKDEENSS 117
            .|.:.|||:.:|::.|.|||||:| ...|...:::..||.:|:.  |.|:: |..:  |::...:
Yeast   120 GVNIEPFNIDDEIKHGVFDKDGNY-IKTENATENDQQDNEEWMNDVINTEEVNRLE--KEQSVKT 181

  Fly   118 DEEKNEPVGKAFNLSMNLMKMVEFMKPGETVKMTLQRLGKQRPVLTTLQRIKQKKAGIVDPKTQE 182
            ...::..|.:|    :||:|.. .:...|||..:|.||.|.|.:..:      ||...:......
Yeast   182 QNSRHYMVHEA----LNLLKFF-LVDENETVLESLGRLNKLRKIAIS------KKNKSLKYVIHG 235

  Fly   183 ISQLTELANEILSKTGNMDIYQDTYESIKAKIADLPGTSKPKVADDIDMYADDFETKELERSKTS 247
            |..|::|.| ||.|.|    :.:.||..:.|:.|   ..:.::.||         :..:...||.
Yeast   236 IELLSDLIN-ILEKKG----FSEVYEYNRLKVQD---AIEEEIFDD---------SSRIVNHKTK 283

  Fly   248 SSDSSKPTTTTSEVTWEFKWSQDETDIQGPFSTEKMLKWSQENYFKNGVYVR 299
                          .|.|||.....:..|.::..:|..| |::||||.|.|:
Yeast   284 --------------LWGFKWLNKLDEYHGLYTNYEMSYW-QKSYFKNSVIVK 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
holn1	NP_609404.2	GYF	260..318	CDD:238027	14/40 (35%)
LIN1	NP_012026.1	GYF	283..340	CDD:214666	14/53 (26%)