Protein Alignment TBC1D16 and MSB3

DIOPT Version :9

• Sequence 1: NP_609403.2
• Gene: TBC1D16 / 34431
• FlyBaseID: FBgn0032249
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: NP_014106.1
• Gene: MSB3 / 855423
• SGDID: S000005237
• Length: 633
• Species: Saccharomyces cerevisiae
• Alignment Length: 462
• Identity: 89/462 - (19%)
• Similarity: 163/462 - (35%)
• Gaps: 149/462 - (32%)

  Fly   241 DSGNSTPADRQKSAMKCRHFSVDLSQMRS--LRLFFNDDNCTSGQL---VIASRESQYKILHFHY 300
            |:||.                 ||.::.|  |.|..:|||....:|   ..|:..:...|.:.|:
Yeast   108 DNGNE-----------------DLEEVHSDDLDLVPDDDNRQRVELEGAASATSANSNGINNTHF 155

  Fly   301 GGLDHLAQVLHQWHCFLHNITSETGQDKFDLPYRHFMVCRPEVKKSEMHPDEGDVKKITTNFFYG 365
            .......|         :|..||...||:.:.|..:.|.|...                    :.
Yeast   156 DRYGFKKQ---------NNYISEAEYDKWWVEYSQYCVRRKHK--------------------WQ 191

  Fly   366 TLLNEKG-QIEDD-------------LLLRKCVFFGGLEKSLRKTVWPFLLKCYSFSSTFEDRAV 416
            .||.:.| .:.||             ..:||     |:....|...|      :.|:...|.
Yeast   192 LLLEKSGLPVTDDSPSRFPSKSERLKRYVRK-----GIPAEWRGNAW------WHFARGQEK--- 242

  Fly   417 LMDIKRQEYEEITR--KRLYSMSPEQQIHFWKTVQ--IVVEKDVVRTDRTNPFFCG-----DDNP 472
             ::..:..|.::.|  |::...:|.:     |.||  .::|:|:.||...|..|..     :..|
Yeast   243 -LNKNKGVYSQLLRKMKQIKKQNPNE-----KQVQDLDIIERDLNRTFPDNIHFQSSLHNKEGPP 301

  Fly   473 NTEVMKNILLNFAVYNTGMSYSQGMSDLLAPVLCEVQNESETFWCFVGLMQRAFFVCTPTDRDVD 537
            ..:.::.:|:.|::||..:.|.|.| :.||.:|....:|...||..|.:          |.|.:.
Yeast   302 IIKSLRRVLVAFSLYNPKIGYCQSM-NFLAGLLLLFLDEERAFWMLVII----------TSRYLP 355

  Fly   538 --HNLS-----------------YLREL---IRIMLPHFYKHLEQHNDSMELL--------FCHR 572
              ||::                 |:.|:   |:..:.|..|:.:..:.|.:.:        |.:|
Yeast   356 GVHNINLEGVNIDQGVLMLCVKEYIPEVWSYIKPSIDHHQKNNKTFSPSNKKVLFNMQKNEFLYR 420

  Fly   573 ----------WLLLCFKREFTEAVVIRMWEACWSNYLTDYFHLFLCLAIIAVYADDVVAQNLRPD 627
                      |.:.||.........:|:|:..:  |...:|...:.||::.:...|:  ..::|.
Yeast   421 LPPITLCTASWFMSCFVGVVPIETTLRIWDCLF--YEESHFLFKVSLAVLKLSEHDL--SKIKPR 481

  Fly   628 EMLLHFS 634
            ...|::|
Yeast   482 NNSLNYS 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBC1D16	NP_609403.2	TBC	387..618	CDD:214540	54/279 (19%)
MSB3	NP_014106.1	COG5210	15..540	CDD:227535	89/462 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900