Protein Alignment TBC1D16 and GYL1

DIOPT Version :9

• Sequence 1: NP_609403.2
• Gene: TBC1D16 / 34431
• FlyBaseID: FBgn0032249
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: NP_013917.1
• Gene: GYL1 / 855230
• SGDID: S000004804
• Length: 720
• Species: Saccharomyces cerevisiae
• Alignment Length: 663
• Identity: 120/663 - (18%)
• Similarity: 210/663 - (31%)
• Gaps: 209/663 - (31%)

  Fly    16 GDERL--DRKIDIAYEDNEILFCKNNVCIHPPTIARDESDI--LHNPGYLTCTTKTFVDQYNSAK 76
            |||:.  |.|:::|..:....|..|.       .|:|...|  ..||
Yeast    41 GDEKAYSDEKVEMATTNASSNFGSNE-------SAKDGESIGAFSNP------------------ 80

  Fly    77 RPTLLLTWIPNSSLCKYTNLNADDCRGQC-NPRSKSPDSRNGYCHVTIPQTIQERDIREEDENAA 140
            ...|:.:.:...|..| |.|.:||...|. ...||..::..   .:|.|......|..||..:|
Yeast    81 HEALMQSKLREESQSK-TILPSDDLSQQLETEESKVEEALK---RITSPPLPPRADCIEESASA- 140

  Fly   141 DMQELKNELQPLLGGQAASIDDLTALLKNNPITSVNITISNPQIENSNISQSFNCITIRPDSNNC 205
                ||:.|.|:|.|.           ||:     ...:..||:....:..:.......|..|..
Yeast   141 ----LKSSLPPVLAGN-----------KND-----QAPLDRPQLPPRQVVNAETLHLKAPHGNAT 185

  Fly   206 SDCTNGSGVGDGPATDNPKWTTP--------ELLAFKHNLEFPDSGNSTPADRQKSAMKCRHFSV 262
            ...:..|.||:..::..|  |.|        :|.|.||.|......|......:.:::||
Yeast   186 PSKSPTSAVGNSSSSTPP--TLPPRRIEDPLDLAAQKHFLASTFKRNMLFYKSEDNSIKC----- 243

  Fly   263 DLSQMRSLRLFFNDDNCTSGQLVIASRESQYKILHFHYGGLDHLAQVLHQWHCFLHNITSETGQD 327
            ||.:        |..|.......|.:.|...::..|       ..:|:..:...|.|
Yeast   244 DLDK--------NILNLKEDSKKINNNEIPEEVSSF-------WLKVIGDYQNILIN-------- 285

  Fly   328 KFDLPYRHFMVCRPEVKKSEMHPDEGDVKKITTNFFYGTLLNEKGQIEDDLLLRKCVFFGGLEKS 392
              |:...||.:.|                                               |:..:
Yeast   286 --DIETLHFQLSR-----------------------------------------------GIPAA 301

  Fly   393 LRKTVWPFLLKCYSFSSTFEDRAVLMDIKRQEYEEITRKRLYSMSPEQQIHFWKTVQIVVEKDVV 457
            .|..||..:    |::            |.:.::.|....|..|:|.....|...::::
Yeast   302 YRLVVWQLV----SYA------------KSKSFDPIYETYLTEMAPFDVQEFENQLKMM------ 344

  Fly   458 RTDRTNPFFCGDDNPNTEV--MKNILLNFAVYNTGMSYSQGMSDLLAPVLCEVQNESETFWCFVG 520
                       |:.|:..|  :.|:|..:.:::....:|..::.::..:|...:.|:..|...|.
Yeast   345 -----------DEVPSEYVKRISNVLKAYLLFDPECEFSTDIAYIINMILDVCEEEANAFGLLVR 398

  Fly   521 LMQ----RAFFVCTPTDRDVDHNLSY-LRELIRIMLPHFYKHLEQH--NDSMELLFCHRWLLLCF 578
            ||:    |..|:.:.::.|:   |.| ...|:....|..:.|:.:.  ..||   |...:....|
Yeast   399 LMKVYGLRLLFLPSASEIDI---LCYKFDRLVEEFYPEIHNHMVEKGVRSSM---FLPGFFTTLF 457

  Fly   579 KREFTEAVVIRMWEACWSNYLTDYFHLFLCLAIIAVYADDVVAQNLRPDEMLLHFSSLAMYMDGQ 643
            :::....:..|:.:..   :|.....:...||.:...:.|             |.  |.|..|..
Yeast   458 QKKLPTEIQPRIGDMV---FLEGIDSIMRILATLLSNSRD-------------HL--LKMGFDDM 504

  Fly   644 LILRKARGLLHQY 656
            |.|.|: |||..|
Yeast   505 LELLKS-GLLDAY 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBC1D16	NP_609403.2	TBC	387..618	CDD:214540	39/239 (16%)
GYL1	NP_013917.1	COG5210	27..569	CDD:227535	120/663 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900