Protein Alignment TBC1D16 and Tbc1d30

DIOPT Version :9

• Sequence 1: NP_609403.2
• Gene: TBC1D16 / 34431
• FlyBaseID: FBgn0032249
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: XP_030101194.1
• Gene: Tbc1d30 / 74694
• MGIID: 1921944
• Length: 909
• Species: Mus musculus
• Alignment Length: 622
• Identity: 131/622 - (21%)
• Similarity: 226/622 - (36%)
• Gaps: 175/622 - (28%)

  Fly   134 EEDENAADMQELKNELQPLLGGQAASIDDLTALLKNNPITSVNITISNPQIE--NSNISQSFNCI 196
            ::.|.||.....:.:|:|...|:.:.    ||.|.:..:|.:.......::.  ....||.   .
Mouse    13 QQSEEAAGHPADEGDLEPQPDGRTSR----TASLVSGLLTELYSCTEEEEVAAGGDRASQG---R 70

  Fly   197 TIRPDSNNCSDCTNGS-------GVGDGPATDNPKWTTPELLAFKHNLEFPDSGNSTPADRQKSA 254
            .:|.||.:.|..|:||       |.||.....       ||                   |::.:
Mouse    71 PLRRDSLDSSTETSGSDAFLGGRGAGDSRVLQ-------EL-------------------RERPS 109

  Fly   255 MKCRHFSVDLSQMRSLRLFFNDDNCTSGQLVIASRESQYKILHFHYGGLD--HLAQVLHQWHCFL 317
            ::.        ||:.|:      ...|.:|....||.:|:|      |:.  .|.:.|.|....|
Mouse   110 LRL--------QMQYLQ------RKDSSELKTVLRELKYRI------GIQSAKLLRQLKQKDRLL 154

  Fly   318 HNITSETGQDKFDLPYRHFMVCRPEVKKSEMHPDEGDVKKITTNFFYGTL---LNEKG-QIEDDL 378
            |.:     |...|:    ...|...|.:.         :::.|...: ||   |.:.| |...|.
Mouse   155 HKV-----QKNCDI----VTACLQAVSQK---------RRVDTKLKF-TLEPSLGQNGFQQWYDA 200

  Fly   379 LLRKCVFFGGLEKSLRKTVWPFLLKCYSFSSTFE-DRAVLMDIKRQEYEEITRKRLYSMSPEQQI 442
            |........|:.|..|:.||..|...|..|...: |:.:     |..:.|.:.....||.
Mouse   201 LKAVARLSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTM-----RFTFNERSNPDDDSMG----- 255

  Fly   443 HFWKTVQIVVEKDVVRTDRTNPFFCGDD-NPNTEVMKNILLNFAVYNTGMSYSQGMSDLLAPVLC 506
                 :|||  ||:.||..::  :||.: ..:..|:|.:||.:|.:|..:.|.||. ::||.::.
Mouse   256 -----IQIV--KDLHRTGCSS--YCGQEAEQDRVVLKRVLLAYARWNKNVGYCQGF-NILAALIL 310

  Fly   507 EVQ--NESETFWCFVGLMQR----AFFVCTPTDRDVDHNLSYLRELIRIMLPHFYKHLEQ----- 560
            ||.  ||.:.....:.|:.:    ::||.......||  ::..|:|:|:.||...:||:.
Mouse   311 EVMEGNEGDALKIMIYLIDKVLPESYFVNNLRALSVD--MAVFRDLLRLKLPELSQHLDTLQRTA 373

  Fly   561 -------HNDSMELLFCHRWLLLCFKREFTEAVVIRMWE---------------ACWSNY----- 598
                   :...:..:|..:|.|..|........|:::|:               |.|:..
Mouse   374 NKESGGGYEPPLTNVFTMQWFLTLFATCLPNHTVLKIWDSVFFEGSEIILRVSLAIWAKLGEQIE 438

  Fly   599 ---LTDYFHLFLCLAIIAVYADDVVAQN-LRPDEMLLHFSSLAMYMDGQLI-LRKARGLLHQYRQ 658
               ..|.|:     ..:.....:::.|: |:..|::....|:|.:...||. ||:.    :.|..
Mouse   439 CCETADEFY-----GTMGRLTQEMLEQDLLQSHELMQTVYSMAPFPFPQLAELREK----YTYNI 494

  Fly   659 LPKIPCTLSGLCKRCGPGMWDSEHRPALECVGHSDDE 695
            .| .|.|:.       |......|..|.:    ||||
Mouse   495 TP-FPATIK-------PTSVSGRHSKARD----SDDE 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBC1D16	NP_609403.2	TBC	387..618	CDD:214540	59/273 (22%)
Tbc1d30	XP_030101194.1	TBC	208..429	CDD:214540	55/242 (23%)
		DUF4682	598..746	CDD:374060

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900