DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TBC1D16 and Tbc1d15

DIOPT Version :9

Sequence 1:	NP_609403.2	Gene:	TBC1D16 / 34431	FlyBaseID:	FBgn0032249	Length:	702	Species:	Drosophila melanogaster
Sequence 2:	XP_006514020.1	Gene:	Tbc1d15 / 66687	MGIID:	1913937	Length:	688	Species:	Mus musculus

Alignment Length:	319	Identity:	109/319 - (34%)
Similarity:	174/319 - (54%)	Gaps:	31/319 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   368 LNEKGQIEDDLLLRKCVFFGGLEKSLRKTVWPFLLKCYSFSSTFEDRAVLMDIKRQEYEEITRKR 432
            |:.:|::.....:::.:|.|||..||||..|.|||..:.:.||.|:|.   .:::|:.:|..|.:
Mouse   326 LDPEGRLVAVESMKQKIFRGGLSHSLRKQAWKFLLGYFPWDSTKEERT---QLQKQKTDEYFRMK 387

  Fly   433 LYSMSPEQQIHFWKTV--------------QIVVEKDVVRTDRTNPFFCGDDNPNTEVMKNILLN 483
            |.          ||:|              :.::||||.||||||.|:.|.|||...::.:||:.
Mouse   388 LQ----------WKSVSEAQEKRNSRLRDYRSLIEKDVNRTDRTNKFYEGQDNPGLILLHDILMT 442

  Fly   484 FAVYNTGMSYSQGMSDLLAPVLCEVQNESETFWCFVGLMQRAFFVCTPTDRDVDHNLSYLRELIR 548
            :.:|:..:.|.|||||||:|:|..::||.:.||||...|.:.........:.:...|..|..|:|
Mouse   443 YCMYDFDLGYVQGMSDLLSPLLYVMENEVDAFWCFASYMDQMHQNFEEQMQGMKTQLIQLSTLLR 507

  Fly   549 IMLPHFYKHLEQHNDSMELLFCHRWLLLCFKREFTEAVVIRMWEACWSNYLTDYFHLFLCLAIIA 613
            ::...|..:||. .||..|.||.||||:.|||||:...::|:||..|:......|||.||.||:.
Mouse   508 LLDSGFCSYLES-QDSGYLYFCFRWLLIRFKREFSFLDILRLWEVMWTELPCKNFHLLLCCAILE 571

  Fly   614 VYADDVVAQNLRPDEMLLHFSSLAMYMDGQLILRKARGL---LHQYRQLPKIPCTLSGL 669
            .....::|::...:|:|.|.:.|:|.:|.:.||.||..:   :.|.::||:..|.:.||
Mouse   572 SEKQQIMAKHYGFNEILKHINELSMKIDVEDILCKAEAISLQMAQCKELPQAVCEILGL 630

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TBC1D16	NP_609403.2	TBC	387..618	CDD:214540	89/244 (36%)
Tbc1d15	XP_006514020.1	DUF3548	10..211	CDD:371881
Tbc1d15	XP_006514020.1	TBC	343..578	CDD:214540	90/248 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1495285at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820