DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TBC1D16 and tbc1d30

DIOPT Version :9

Sequence 1:	NP_609403.2	Gene:	TBC1D16 / 34431	FlyBaseID:	FBgn0032249	Length:	702	Species:	Drosophila melanogaster
Sequence 2:	XP_021331078.1	Gene:	tbc1d30 / 569334	ZFINID:	ZDB-GENE-030131-2064	Length:	1063	Species:	Danio rerio

Alignment Length:	235	Identity:	52/235 - (22%)
Similarity:	96/235 - (40%)	Gaps:	60/235 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   388 GLEKSLRKTVWPFLLKCYSFSST----------FEDRAVLMDIKRQEYEEITRKRLYSMSPEQQI 442
            |:.|..||.||..|...|..|.:          |.||:                     :|:..
Zfish   239 GIPKEWRKRVWLTLADQYLHSISIDWEKTMRFAFNDRS---------------------NPDDD- 281

  Fly   443 HFWKTVQIVVEKDVVRTDRTNPFFCGDD-NPNTEVMKNILLNFAVYNTGMSYSQGMSDLLAPVLC 506
                ::.|.:.||:.||..::  :||.: ..:..|:|.:||.:|.:|..:.|.||. ::||.::.
Zfish   282 ----SLGIQIVKDLHRTGCSS--YCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGF-NVLAALIL 339

  Fly   507 EVQ--NESETFWCFVGLMQR----AFFVCTPTDRDVDHNLSYLRELIRIMLPHFYKHLE------ 559
            ||.  ||.:.....:.|:.:    ::|........||  ::..|:|:|:.||...:||.
Zfish   340 EVTEGNEGDALKVMIYLIDKVLPDSYFANNLRALSVD--MAVFRDLLRLKLPELSQHLHHLQKVA 402

  Fly   560 ------QHNDSMELLFCHRWLLLCFKREFTEAVVIRMWEA 593
                  .:...:..:|..:|.|..|........|:::|::
Zfish   403 NREAGGSYEPPLTNVFTMQWFLTMFATCLPHHTVLKIWDS 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TBC1D16	NP_609403.2	TBC	387..618	CDD:214540	52/235 (22%)
tbc1d30	XP_021331078.1	TBC	239..458	CDD:214540	52/235 (22%)
		DUF4682	625..775	CDD:318030
		HrpB7	733..>820	CDD:330448
		Herpes_BLLF1	<825..>973	CDD:330317
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900