Protein Alignment TBC1D16 and TBC1D25

DIOPT Version :9

• Sequence 1: NP_609403.2
• Gene: TBC1D16 / 34431
• FlyBaseID: FBgn0032249
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: NP_001335191.1
• Gene: TBC1D25 / 4943
• HGNCID: 8092
• Length: 704
• Species: Homo sapiens
• Alignment Length: 422
• Identity: 120/422 - (28%)
• Similarity: 182/422 - (43%)
• Gaps: 96/422 - (22%)

  Fly   253 SAMKC--------RHFSVDLSQMRSLRLFFNDDNCTSGQLVIASRESQYKILHFHYGGLDHLAQ- 308
            |..||        |.|:|| .|:.||       :.....|:.|...|..|.....|.|.|.|.|
Human    55 SPQKCESFLPPEFRSFAVD-PQITSL-------DVLQHILIRAFDLSGKKNFGISYLGRDRLGQE 111

  Fly   309 ----VLHQWHCFLHNITSETGQDKFDLPYRHFMVCRPEVKKSEMHP--DEGDV------------ 355
                :|..|..          ...|....:.::..|.:::.||..|  ::.|:
Human   112 VYLSLLSDWDL----------STAFATASKPYLQLRVDIRPSEDSPLLEDWDIISPKDVIGSDVL 166

  Fly   356 -----KKITT------------------------NFFYG----------------TLLNEKGQIE 375
                 ..:||                        ::.||                |.||.:||:.
Human   167 LAEKRSSLTTAALPFTQSILTQVGRTLSKVQQVLSWSYGEDVKPFKPPLSDAEFHTYLNHEGQLS 231

  Fly   376 DDLLLRKCVFFGGLEKSLRKTVWPFLLKCYSFSSTFEDRAVLMDIKRQEYEEITRKRLYSMSPEQ 440
            ....||..::.||:|.||||.||.:||..|....|..:|...|..|.:|||::..:.....:||
Human   232 RPEELRLRIYHGGVEPSLRKVVWRYLLNVYPDGLTGRERMDYMKRKSREYEQLKSEWAQRANPE- 295

  Fly   441 QIHFWKTVQIVVEKDVVRTDRTNPFFCG-DDNPNTEVMKNILLNFAVYNTGMSYSQGMSDLLAPV 504
            .:.|   ::..|.|||:||||.:|::.| :|.|:...:.::|..:||.:..:||.||||||.:|:
Human   296 DLEF---IRSTVLKDVLRTDRAHPYYAGPEDGPHLRALHDLLTTYAVTHPQVSYCQGMSDLASPI 357

  Fly   505 LCEVQNESETFWCFVGLMQRAFFVCTPTDRDVDHNLSYLRELIRIMLPHFYKHLEQHNDSMELLF 569
            |..:.:|...|.||.|:|:|......|..|.:....::|:.|:|...|.||::| |...:.:|.|
Human   358 LAVMDHEGHAFVCFCGIMKRLAANFHPDGRAMATKFAHLKLLLRHADPDFYQYL-QEAGADDLFF 421

  Fly   570 CHRWLLLCFKREFTEAVVIRMWEACWSNYLTD 601
            |:|||||..||||.....:||.|..||:...|
Human   422 CYRWLLLELKREFAFDDALRMLEVTWSSLPPD 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBC1D16	NP_609403.2	TBC	387..618	CDD:214540	82/216 (38%)
TBC1D25	NP_001335191.1	TBC	241..470	CDD:214540	82/218 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1495285at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820