Protein Alignment TBC1D16 and tbc1d15

DIOPT Version :9

• Sequence 1: NP_609403.2
• Gene: TBC1D16 / 34431
• FlyBaseID: FBgn0032249
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: XP_005159143.1
• Gene: tbc1d15 / 492676
• ZFINID: ZDB-GENE-041111-251
• Length: 665
• Species: Danio rerio
• Alignment Length: 566
• Identity: 147/566 - (25%)
• Similarity: 239/566 - (42%)
• Gaps: 118/566 - (20%)

  Fly   202 SNNCSDCTNGSGVGD--GPATDNP------------KWTTPELLAFKHNLEFPDSGNSTPADRQK 252
            ||....|.:.|.|.:  ..:.:||            :|.....::|:..:.....|.|...:.|.
Zfish    57 SNMLCACKDSSSVVEWTQSSEENPHRPVDHQLSYETEWDMINAVSFRRKVHANGDGGSNHVNEQN 121

  Fly   253 SAMKCRHFSVDLSQMRSLRLFFNDDNCTSGQLVIASR---ESQYKILHFHYGG----LDHLAQVL 310
            .    |.||.::..:||:.:     .| .|...:..|   .:....:|||.||    ||.|.:.:
Zfish   122 K----RAFSFNVCDLRSVTV-----KC-EGWSYLTFRLKDGTALPAIHFHQGGSKAFLDSLRKSV 176

  Fly   311 H------------------QWHCFLHNITSETG----QDKFDL-PYRH------------FMVCR 340
            .                  .:.....|:..:|.    |.||.. ||..            |...|
Zfish   177 QINESPDDESVLIVSTYSKAFSQSFENLLDDTNYGFVQQKFKKDPYTTTLGGFSKVTNYLFDAFR 241

  Fly   341 PEVKKSEMHPDEGDVKKITTNFFYGTLLNE----------------------------------- 370
            ....:.:..|.| :|..:......|..:|:
Zfish   242 APELECQQRPAE-EVADVLGELIPGLEINQQEEPGFEVITRLDLGPRPEMQRTGPVTMEEWAKYQ 305

  Fly   371 --KGQIEDDLLLRKCVFFGGLEKSLRKTVWPFLLKCYSFSSTFEDRAVLMDIKRQEYEEITRKRL 433
              :|::.:...|:..:|.|||..::||..|.|||..:.:|||.|:|.:|...|..||   .|.:|
Zfish   306 DLEGRMTNLPHLKDAIFKGGLCHAVRKEAWKFLLGYFPWSSTHEERKLLQKRKTDEY---FRMKL 367

  Fly   434 Y--SMSPEQQ-----IHFWKTVQIVVEKDVVRTDRTNPFFCGDDNPNTEVMKNILLNFAVYNTGM 491
            .  |:|.||:     :..:::   ::||||.||||.|.|:.|.|||...::.:||:.:.:|:..:
Zfish   368 QWKSVSEEQERRNSRLRDYRS---LIEKDVNRTDRNNKFYEGLDNPGLILLHDILMTYCMYDFDL 429

  Fly   492 SYSQGMSDLLAPVLCEVQNESETFWCFVGLMQRAFFVCTPTDRDVDHNLSYLRELIRIMLPHFYK 556
            .|.|||||||:|:|..::||.:.|||||..|...........:.:...|..|..|:|::...|:.
Zfish   430 GYVQGMSDLLSPILFVMENEVDAFWCFVSFMDEMHENFEEQMQGMKTQLIQLSTLLRLLDLAFWN 494

  Fly   557 HLEQHNDSMELLFCHRWLLLCFKREFTEAVVIRMWEACWSNYLTDYFHLFLCLAIIAVYADDVVA 621
            :||. .||..|.||.||||:.||||.....|:|:||..|:......|||.:|.||:......::.
Zfish   495 YLEA-QDSGYLYFCFRWLLIRFKRELHFQDVLRLWEVMWTRLPCQNFHLLVCCAILDSEKQKIMD 558

  Fly   622 QNLRPDEMLLHFSSLAMYMDGQLILRKARGLLHQYRQLPKIPCTLS 667
            :....:|:|.|.:.|:|.:|.:.||.|:..:..|.:....:|.::|
Zfish   559 RKYGFNEILKHINELSMKLDIEEILSKSESICMQIKSCKDLPHSVS 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBC1D16	NP_609403.2	TBC	387..618	CDD:214540	90/237 (38%)
tbc1d15	XP_005159143.1	DUF3548	4..220	CDD:192931	33/172 (19%)
		TBC	322..557	CDD:214540	91/241 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1495285at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820