Protein Alignment TBC1D16 and tbc1d16

DIOPT Version :10

• Sequence 1: NP_609403.2
• Gene: TBC1D16 / 34431
• FlyBaseID: FBgn0032249
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: XP_012814267.2
• Gene: tbc1d16 / 448159
• XenbaseID: XB-GENE-986691
• Length: 727
• Species: Xenopus tropicalis
• Alignment Length: 746
• Identity: 321/746 - (43%)
• Similarity: 439/746 - (58%)
• Gaps: 99/746 - (13%)

  Fly     1 MPIGSIIKKASS----FIL-----GDERLDRKIDIAYEDNEILFCKNNVCIHPPTIARDESDILH 56
            |.:|.::::|||    |:.     |...:        .|.||:|.|||||:|||.:.:|...  |
 Frog     1 MSLGRLLRRASSKASDFLTLSSGGGSSSI--------LDGEIIFSKNNVCVHPPELLQDVGS--H 55

  Fly    57 NPGYLTCTTKTFVDQYNSAKRPTLLLTWIPNSSLCKYTNLNADDCRGQCNPRSKSPDSRNGYCHV 121
            :||||....:.  |::...   ||:|.|:|||.:.:...........:.:|..|:|..||.....
 Frog    56 HPGYLCVYMEK--DEFLGT---TLILAWVPNSRIQRQDEEALRYITPESSPIRKNPRKRNRQPPG 115

  Fly   122 TIPQT------IQERDI-RE------------------------EDENAADMQELKNELQPLLGG 155
            :.|.|      |.:.|: ||                        |||.:.|:...:......|..
 Frog   116 SAPTTRSKPAIISKEDVGREVNSPTERDPSYGSAEGVEEGTEQGEDERSLDLSSDEVSKDSTLDS 180

  Fly   156 QAASIDDLTALLKNNPIT-SVNITISNPQIENSNISQSFNCITIRPDSNNCSDC---TNGSGVGD 216
            .:.:......|   :||: ::..:.|:..:||.|..:|.:.::....|.|.:..   .||.||
 Frog   181 DSDAFSSPFCL---SPISEALGESSSSVFLENENRDESNSHMSSYASSLNANSQLPEINGQGV-- 240

  Fly   217 GPATDNPKWTTPE-LLAFKHNLEFPDSGNSTPADRQKSAMKCRHFSVDLSQMRSLRLFFNDDNCT 280
             ||    ||...: |||.:..                    |..|.|||.||||||.||:|:.||
 Frog   241 -PA----KWEEQQKLLALEQT--------------------CGVFRVDLGQMRSLRFFFSDEACT 280

  Fly   281 SGQLVIASRESQYKILHFHYGGLDHLAQVLHQW-HCFLHNI-TSETGQDKFDLPYRHFMVCRPEV 343
            |||||:||||||||:.|||:|||..|::|..|| :|....: ..:..:||..|   ||.:.||.:
 Frog   281 SGQLVVASRESQYKVFHFHHGGLGKLSEVFQQWKYCRETQLKEQQVTEDKTCL---HFSIQRPNL 342

  Fly   344 KKSEMHPDEGDVKKITTNFFYGTLLNEKGQIEDDLLLRKCVFFGGLEKSLRKTVWPFLLKCYSFS 408
            ..||.||:||..:::....:. ..|||.||:|::..|||.:||||::.|||..||||||..|.:.
 Frog   343 PSSESHPEEGMYRRLDVTSWL-EHLNEVGQVEEEYKLRKLIFFGGIDPSLRGEVWPFLLGYYPWE 406

  Fly   409 STFEDRAVLMDIKRQEYEEITRKRLYSMSPEQQIHFWKTVQIVVEKDVVRTDRTNPFFCGDDNPN 473
            .|.|||..|...:|:||.:|.:||: ||||..|..|||.||..|:||||||||:|.||.|:||||
 Frog   407 ITSEDREALRVHRREEYSQIQKKRV-SMSPTAQKEFWKNVQFTVDKDVVRTDRSNQFFRGEDNPN 470

  Fly   474 TEVMKNILLNFAVYNTGMSYSQGMSDLLAPVLCEVQNESETFWCFVGLMQRAFFVCTPTDRDVDH 538
            .|.|:.||||:|||:.|:.||||||||:||:|.||.:||:||||||||||...|:.:|.|..::.
 Frog   471 VESMRRILLNYAVYSPGVGYSQGMSDLVAPILAEVLDESDTFWCFVGLMQNTIFISSPRDEYMEK 535

  Fly   539 NLSYLRELIRIMLPHFYKHL-EQHNDSMELLFCHRWLLLCFKREFTEAVVIRMWEACWSNYLTDY 602
            .|.|||||:|::.|.||:|| ....|.:::||||||:||||||||.::..:|||||||::|.|||
 Frog   536 QLLYLRELLRLVHPRFYQHLYSLGEDGLQMLFCHRWILLCFKREFPDSEALRMWEACWAHYQTDY 600

  Fly   603 FHLFLCLAIIAVYADDVVAQNLRPDEMLLHFSSLAMYMDGQLILRKARGLLHQYRQLPKIPCTLS 667
            ||||||:|||.:|.|||:.|.|..|:||||||:|||:|:|:|:|||||.||:|:|.||:|||:|.
 Frog   601 FHLFLCVAIIVLYGDDVIEQQLPTDQMLLHFSNLAMHMNGELVLRKARSLLYQFRLLPRIPCSLH 665

  Fly   668 GLCKRCGPGMWDSEHRPALECVG-HSDDEKC 697
            .|||.|.||||||.:.|.:||.| ||:.|.|
 Frog   666 DLCKLCSPGMWDSGYIPPVECTGHHSESESC 696

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBC1D16	NP_609403.2	TBC	387..618	CDD:214540	136/231 (59%)
tbc1d16	XP_012814267.2	TBC	385..613	CDD:214540	135/228 (59%)