Protein Alignment TBC1D16 and tbc1d15

DIOPT Version :9

• Sequence 1: NP_609403.2
• Gene: TBC1D16 / 34431
• FlyBaseID: FBgn0032249
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: NP_989223.1
• Gene: tbc1d15 / 394831
• XenbaseID: XB-GENE-1008350
• Length: 666
• Species: Xenopus tropicalis
• Alignment Length: 593
• Identity: 162/593 - (27%)
• Similarity: 255/593 - (43%)
• Gaps: 123/593 - (20%)

  Fly   192 SFNCITIRPDSNNCSDCT---NGSGVGDGPATDNPKWTTPELLAFKHNLEFPDSGNSTPADRQKS 253
            |.|.:....||::..:.|   .|..:.|...:...:|.....::||.. :|.:.|..:|.:.|..
 Frog    58 SSNILCAAKDSSSVVEWTTKERGMHLPDHQNSYEAEWDMVNTVSFKKK-QFANGGVQSPLNSQSK 121

  Fly   254 AMKCRHFSVDLSQMRSLRLFFNDDN--------CTSGQLVIASRESQYKILHFHYGGLDHLAQVL 310
                ..|...|:.::|::.  |.:.        |....:|:.:       ||||.||.:.|.:.|
 Frog   122 ----WSFLFSLADLKSIKQ--NKEGMGWSYFVFCLKDDVVLPA-------LHFHQGGSELLLECL 173

  Fly   311 HQWHCFLHNITSETGQD--------------------------------KFDLPYRH-------- 335
            .:     |.:..|:.||                                |.| ||..
 Frog   174 GK-----HVMFCESEQDGRILLVSCQNNSLSQSFENLLEESTYSLIQKLKKD-PYTATLASFSKV 232

  Fly   336 ----FMVCRPEVKKSEMHPDE---------GDVK---------KITTNFFYGTL----------- 367
                |...|.....::..|.|         .|:|         ::.|....||.
 Frog   233 TNYLFDTIRGSDPVTQRRPREEMAFLGDAIQDLKINQQEESGFEVITRIDVGTRPEVHRRDPMST 297

  Fly   368 ------LNEKGQIEDDLLLRKCVFFGGLEKSLRKTVWPFLLKCYSFSSTFEDRAVLMDIKRQEYE 426
                  ::.:|:|.:...::..:|.|||..:|||.||.|||..:.:.||.|:||.|...|..||
 Frog   298 AEWEANIDHEGRICNVDRIKNMIFKGGLCHALRKEVWKFLLGYFPWDSTREERAHLQKRKTDEY- 361

  Fly   427 EITRKRLY--SMSPEQQIHFWK--TVQIVVEKDVVRTDRTNPFFCGDDNPNTEVMKNILLNFAVY 487
              .|.:|.  |:|.||:....|  ..:.::||||.||||||.|:.|.|||...::.:||:.:.:|
 Frog   362 --FRMKLQWKSVSEEQENRNSKLRDYRSLIEKDVNRTDRTNKFYEGPDNPGLNLLHDILMTYCMY 424

  Fly   488 NTGMSYSQGMSDLLAPVLCEVQNESETFWCFVGLMQRAFFVCTPTDRDVDHNLSYLRELIRIMLP 552
            :..:.|.|||||||:|||..::||.:.|||||..|.:.........:.:...|.:|..|:|::..
 Frog   425 DFDLGYVQGMSDLLSPVLYVMENEVDAFWCFVSYMDQMHQNFEEQMQGMKTQLVHLSTLLRLLDS 489

  Fly   553 HFYKHLEQHNDSMELLFCHRWLLLCFKREFTEAVVIRMWEACWSNYLTDYFHLFLCLAIIAVYAD 617
            .|..:||. .||..|.||.||||:.|||||.....:|:||..|::.....|||.:|.||:.....
 Frog   490 GFCSYLES-QDSGYLYFCFRWLLIRFKREFNFQDTLRLWEVIWTDLPCQNFHLLICCAILESEKQ 553

  Fly   618 DVVAQNLRPDEMLLHFSSLAMYMDGQLILRKARGL---LHQYRQLPKIPCTLSGLCKR--CGPGM 677
            .::.|:...:|:|.|.:.|:|.:|...:|.||..:   :.:.:.||...|.:.|:...  .||..
 Frog   554 VIMEQHFGFNEILKHINELSMKLDVNDVLSKAEAISLQMMKCKDLPLNVCDVIGIKNNGVAGPNE 618

  Fly   678 WDSEHRPA 685
            ..||...|
 Frog   619 ATSEENLA 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBC1D16	NP_609403.2	TBC	387..618	CDD:214540	95/234 (41%)
tbc1d15	NP_989223.1	DUF3548	8..205	CDD:371881	32/165 (19%)
		TBC	321..556	CDD:214540	96/238 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1495285at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010