Protein Alignment TBC1D16 and Tbc1d14

DIOPT Version :9

• Sequence 1: NP_609403.2
• Gene: TBC1D16 / 34431
• FlyBaseID: FBgn0032249
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: NP_001106836.1
• Gene: Tbc1d14 / 360956
• RGDID: 1309993
• Length: 714
• Species: Rattus norvegicus
• Alignment Length: 614
• Identity: 126/614 - (20%)
• Similarity: 212/614 - (34%)
• Gaps: 164/614 - (26%)

  Fly   105 CNP------------RSKSPDSRNGYCHVTIPQTIQERDIREEDENAADMQELKNELQPLLGGQA 157
            |.|            |..|...|.||..|.:.....:...|.:|.:...:..|..||...|  ..
  Rat   131 CTPSAPTGSEREQAVRKSSTFPRTGYDSVKLYSPTSKALSRSDDVSVCSVSSLGTELSTTL--SV 193

  Fly   158 ASIDDLTALLKNNPITSVNITISN---PQIENSNISQSFNCITIRPDSN-NCSDCTNGSGVGDGP 218
            ::.|.|..::.:|  :|..:|:.|   ||..:..:|      :|:..|: :..||...:..|...
  Rat   194 SNEDILDLMVTSN--SSAIVTLENDDDPQFTDVTLS------SIKETSDLHQQDCVAETEEGRKL 250

  Fly   219 ATDNP--KWTTPELLAFKHNLEFPDSGNSTPADRQKSAMKCRHFSVDLSQMRSLRLFFN------ 275
            ....|  .:.|..|||.|.|...         |||:          ||    ..:||..
  Rat   251 RLLQPFSHFFTRNLLARKQNARL---------DRQR----------DL----GWKLFGKVPLRET 292

  Fly   276 ------------DDNCTSGQLVIASRESQYKILHFHYGGLDHLAQVLHQWHCFLHNITSETGQDK 328
                        :|.........:.:::..|.|.|.  .|...|.:|......|....:|..| |
  Rat   293 AQKDSKKTQKEYEDKAGRPSRPPSPKQNVRKNLDFE--PLSTTALILEDRPANLPAKPAEEAQ-K 354

  Fly   329 FDLPYRHFMVCRPEVKKSEMHPDEGDVKKITTNFFYGTLLNEKGQIEDDL----------LLRK- 382
            ....|...:|   :.||.|:...:...|:          |.|:.::|:.:          :|..
  Rat   355 HRQQYEEMVV---QAKKRELKEAQRRKKQ----------LEERCKVEESIGNAVLTWNNEILPNW 406

  Fly   383 ----C------VFFGGLEKSLRKTVWPFLLKCYSFSSTFEDRAVLMDIKRQEYEEITRKRLYSMS 437
                |      :::.|:..|:|..||...:. ...:.|.|    |.||.....:|    |..|:|
  Rat   407 ETMWCSKKVRDLWWQGIPPSVRGKVWSLAIG-NELNITHE----LFDICLARAKE----RWRSLS 462

  Fly   438 P-----EQQIHFWKTVQIVVEKDVVRTD--RTNPFFC--GDDNPNTEVMKNILLNFAVYNTGMSY 493
            .     |.:...:.........::::.|  ||.|..|  ....|..:::.:||..:..|...:.|
  Rat   463 TGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQGGPYHDMLHSILGAYTCYRPDVGY 527

  Fly   494 SQGMSDLLAPVLCEVQNESETFWCFVGLM----QRAFFVCTPTDRDVDHNL-----SYLRELIRI 549
            .|||| .:|.||....:.::.|..|..|:    |.|||       .|||.|     :........
  Rat   528 VQGMS-FIAAVLILNLDTADAFIAFSNLLNKPCQMAFF-------RVDHGLMLTYFAAFEVFFEE 584

  Fly   550 MLPHFYKHLEQHNDSMELLFCHRWLLLCFKREFTEAVVIRMWEA-C-----------------WS 596
            .||..:.|.:::|.:.: ::...|:...:.:.....:..|:|:. |                 :.
  Rat   585 NLPKLFAHFKKNNLTAD-IYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGILKLFE 648

  Fly   597 NYLT--DYFH--LFLCLAIIAVYADDVVA 621
            :.||  |:.|  .||......:.||||.|
  Rat   649 DILTRMDFIHSAQFLTRLPEDLPADDVFA 677

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBC1D16	NP_609403.2	TBC	387..618	CDD:214540	58/270 (21%)
Tbc1d14	NP_001106836.1	DUF4207	147..384	CDD:290615	57/285 (20%)
		TBC	419..651	CDD:214540	51/249 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810