Protein Alignment TBC1D16 and Rabgap1l

DIOPT Version :9

• Sequence 1: NP_609403.2
• Gene: TBC1D16 / 34431
• FlyBaseID: FBgn0032249
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: XP_006250167.1
• Gene: Rabgap1l / 304914
• RGDID: 1304620
• Length: 1051
• Species: Rattus norvegicus
• Alignment Length: 856
• Identity: 165/856 - (19%)
• Similarity: 271/856 - (31%)
• Gaps: 317/856 - (37%)

  Fly     7 IKKASSFILGDERLDRKIDIAYEDNEILFCKNNVCIHPPTIARDESDILHNPGYLTCTTKTFVD- 70
            :|.||:   |||:|::.::....|:|    |....:  |...:..|:|         :..:|.|
  Rat    45 LKIASN---GDEQLEKAMEEILRDSE----KGQSSL--PVDGQGSSEI---------SDHSFGDV 91

  Fly    71 QYNSAKRPTLLLTWIPNSSLCKYTNLNADDCRGQCNPRSKSPD-------------SRNGYCHVT 122
            ..:.:.:|.|.|...|::     |.::        .||..||.             :..|...|:
  Rat    92 PASQSNKPPLQLILDPSN-----TEIS--------TPRPSSPSGFPEEDSVLFNKLTYLGCMKVS 143

  Fly   123 IPQTIQERDIREEDENAADMQELKNELQ-PLLGGQAASIDDLTALLKNNPITSVNI--TISNPQI 184
            .|        |.|.|....|..::...| |..         :|..:.|.|..||.|  ..||.:|
  Rat   144 SP--------RSEGEALRAMATMRASSQYPFA---------VTLYVPNVPEGSVRIIDQSSNVEI 191

  Fly   185 ---------------------------ENSNISQSFN-------------------CITIRPDSN 203
                                       |:|:.|:.|.                   |...:..|.
  Rat   192 ASFPIYKVLFCARGHDGTTESNCFAFTESSHGSEEFQIHVFSCEIKEAVSRILYSFCTAFKRSSR 256

  Fly   204 NCSDCTNGSGVGDG--PATDNPKWTTPELLAFKHNLEFPD---SGNSTPA--DRQKSAMKCRH-- 259
            ..||      |.|.  |..|:      ::..|..:||..:   .||.:|.  ||.|...|.:.
  Rat   257 QVSD------VKDSIIPTPDS------DVFTFSVSLEVKEDDGKGNFSPVPKDRDKFYFKIKQGI 309

  Fly   260 ---FSVDLSQMRSLRLFFNDDNCTSGQLVIASRESQYKILHF--------HYGGLDHLAQVLHQW 313
               ..:.:.|:.:..|..  :.| .|.|:...|..:...:|.        .|.|..::  :...|
  Rat   310 EKKVVITVQQLSNKELAI--ERC-FGMLLSPGRNVKNSDMHLLDMESMGKSYDGRAYV--ITGMW 369

  Fly   314 H----CFLHNITSETGQDK-------FDL-------PYRHFM--VCR------------------ 340
            :    .|| .:..||.:||       .|:       |.|..:  |.|
  Rat   370 NPNAPIFL-ALNEETPKDKRVYMTVAVDMVVTEVVEPVRFLLETVVRVYPANERFWYFSRKTFTE 433

  Fly   341 -----------------------------------------------PEVKKSEMHPDE------ 352
                                                           |:..::|...|.
  Rat   434 TFFMRLKQSEGKGHSSAGDAIYEVVSLQRESDKEEPVTPTSGGGPASPQEDEAEEESDNELSSGT 498

  Fly   353 GDVKKITTN---FFYGTLLNEKGQIEDDLLLR----KCVFFGGLEKSLRKTVWPFLLKCYSFSST 410
            |||.|....   :.:|.||   |:..::|..|    ..:...|:.::||..||..|..|:
  Rat   499 GDVSKDCPEKILYSWGELL---GRWHNNLNARPKGLPTLVKSGVPEALRAEVWQLLAGCH----- 555

  Fly   411 FEDRAVLMDIKRQEYEEITRKRLYSMSPEQQIHFWKTVQIVVEKDVVRTDRTNPFFCGDDNPNTE 475
              |...::|    :|..:..|.             ...:.|:.:|:.||...:.:|........|
  Rat   556 --DNQAMLD----KYRILITKD-------------SAQESVITRDIHRTFPAHDYFKDTGGDGQE 601

  Fly   476 VMKNILLNFAVYNTGMSYSQGMSDLLAPVLCEVQNESETFWCFVGLMQRAFFVCTPTDRDVDHN- 539
            .:..|...::||:..:.|.||.| .||.||.....|.:.|...|.:|.:...      ||:..|
  Rat   602 SLYKICKAYSVYDEDIGYCQGQS-FLAAVLLLHMPEEQAFCVLVNIMYKYKL------RDLYKNN 659

  Fly   540 -------LSYLRELIRIMLPHFYKH-----LEQHNDSMELLFCHRWLLLCFKREFTEAVVIRMWE 592
                   ...|.:|::..||..|.|     ||.|      ::..:|.|..|..:|...:|..:.:
  Rat   660 FEDLHCKFYQLEKLMQEQLPDLYSHFCDLNLEAH------MYASQWFLTLFTAKFPLCMVFHIID 718

  Fly   593 ACWSNYLTDYFHLFLCLAIIAVYADDVVAQNLRPDEMLLHFSSLAMYMDGQLILR-----KARGL 652
            ......|...||  :.||::....:|:    |:.|     |.....:...||..|     .||.|
  Rat   719 LLLCEGLNIIFH--VALALLKTSKEDL----LQAD-----FEGALKFFRVQLPKRYRAEENARRL 772

  Fly   653 LHQYRQLPKIP 663
            :.|...: |:|
  Rat   773 MEQACNI-KVP 782

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBC1D16	NP_609403.2	TBC	387..618	CDD:214540	54/243 (22%)
Rabgap1l	XP_006250167.1	PTB_Rab6GAP	129..257	CDD:269922	24/144 (17%)
		DUF3694	340..421	CDD:289256	15/83 (18%)
		RabGAP-TBC	541..744	CDD:278964	54/245 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810