Protein Alignment TBC1D16 and Sgsm2

DIOPT Version :9

• Sequence 1: NP_609403.2
• Gene: TBC1D16 / 34431
• FlyBaseID: FBgn0032249
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: XP_006246802.1
• Gene: Sgsm2 / 303304
• RGDID: 1306957
• Length: 1050
• Species: Rattus norvegicus
• Alignment Length: 944
• Identity: 190/944 - (20%)
• Similarity: 298/944 - (31%)
• Gaps: 404/944 - (42%)

  Fly     2 PIGSIIKKASSFILGDERL----DRKIDIAYEDN--EILFCKNNVCIHPPTIARDESDILHNPGY 60
            |...|.|:.||....::||    ...::..::::  .:|:.||||.:.|      :.|:...|||
  Rat   221 PALGIRKRHSSGSASEDRLAACAREYVESLHQNSRTRLLYGKNNVLVQP------KEDMEAVPGY 279

  Fly    61 LTCTTKTFVDQYNSAKRPTLLLTWIPNSSL---------------------------CKYTN--- 95
            |:.        :.||:  .|.|.|.||..:                           |.:.:
  Rat   280 LSL--------HQSAE--NLTLKWTPNQLMNGTLGDSELEKSVYWDYALVVPFSQIVCVHCHQQK 334

  Fly    96 --------------------------LNADDC-------RGQCNPRSKSPDSRNGYCHVTIPQTI 127
                                      |:...|       |||..|...:...:.    ...|:..
  Rat   335 SGGTLVLVSQDGIQRPPLHFPQGGHLLSFLSCLENGLLPRGQLEPPLWTQQGKG----KVFPKLR 395

  Fly   128 QERDIREEDE------NAADM-----------QELKNELQPLLGGQAASIDD-------LTALLK 168
            :...||..|.      .|.|.           :.:......|...:|||:||       |.|:|
  Rat   396 KRSSIRSIDAEELGVGRATDYVFRIIYPGHRHEHITINYHHLAASRAASVDDDEEEEDKLHAML- 459

  Fly   169 NNPITSVNITISNP------QIENSNISQSFNCITIRPDSNNCSDCTNGSGVGDGPATDNPKWTT 227
             :.|.|.|:|..||      .||......|.....:.|      .|:.||.....|::.:|
  Rat   460 -SMICSRNLTAPNPMKDAGDMIEMQGFGPSLTAWHLEP------LCSQGSSCLSCPSSSSP---- 513

  Fly   228 PELLAFKHNLEFPDSGNSTPADRQKSAMKCRHFSVDLSQMRSLRLFFNDDNCTSGQLVIASRESQ 292
                      ..|.|..|...||                 ..|||.     |.|.:..|.||.
  Rat   514 ----------YAPPSHCSCTPDR-----------------LPLRLL-----CESMKRQIVSRA-- 544

  Fly   293 YKILHFHYGGL----------DHLAQVLHQWHCFLHNITSETGQDKFDLPYRHFMVCRPEVKKSE 347
                  .||.|          .||:.::|      |||          :|
  Rat   545 ------FYGWLAYCRHLSTVRTHLSALVH------HNI----------IP--------------- 572

  Fly   348 MHPDE------GDVKKITTNFFYGTLLNEKGQIEDDLLLRKCVFFGGLEKSLRKTVWPFLLKCYS 406
              ||.      |..|.:.:.:     ..:|...::..|||: |::||:|..:||.||||||..|.
  Rat   573 --PDRPPGASGGLTKDVWSKY-----QKDKKNYKELELLRQ-VYYGGVEHEIRKDVWPFLLGHYK 629

  Fly   407 FSST----------------------------------------------------------FED 413
            |..:                                                          ..|
  Rat   630 FGMSKKEMEQVDAAVAARYQQVLAEWKACEVVVRQREREAHPATLTKFSSGSSIDSHVQRLVHRD 694

  Fly   414 RAVLMDI-------------------KRQEYEE-----------------------ITRKRLYSM 436
            ..:..|:                   .:||.|.                       :...|.||:
  Rat   695 STISNDVFISVDDLEPPGPQDPEDSKPKQEREPGAGTPGTAAAEQQSVEFESPDSGLPSSRNYSV 759

  Fly   437 S----------------------------------------PEQQ-------------------- 441
            :                                        |:|:
  Rat   760 ASGIQSSLDEAQSVGFEEDGAGEEGSEEPATAAHTFLGPHDPDQEKLAPASELEGGEELTAVCAA 824

  Fly   442 ---IHFWKTVQI---VVEKDVVRTDRTNPFFCGDDNPNTEVMKNILLNFAVYNTGMSYSQGMSDL 500
               |....||.:   .::|||.|.||...:|   ..||.|.:::|:.::...:..|.|.|||.||
  Rat   825 TYTIELLDTVALNLHRIDKDVQRCDRNYWYF---TTPNLERLRDIMCSYVWEHLDMGYVQGMCDL 886

  Fly   501 LAPVLCEVQNESETFWCFVGLMQRA---FFVCTPTDRDVDHNLSYLRELIRIMLPHFYKHLEQHN 562
            |||:|..:.|:...:.||..||:|.   |    |....:|.:.:.:|.||:|:....::.:.|:.
  Rat   887 LAPLLVILDNDQLAYSCFSHLMKRMSQNF----PNGGAMDTHFANMRSLIQILDSELFELMHQNG 947

  Fly   563 DSMELLFCHRWLLLCFKREFTEAVVIRMWEACWS--NYLTDYFHLFLCLAIIAVYADDVVAQNLR 625
            |.....||:||.||.||||.....|..:||..|:  :..:::|.||:.||::..|.:.:...|:.
  Rat   948 DYTHFYFCYRWFLLDFKRELLYEEVFAVWEVIWAARHISSEHFVLFIALALVEAYREIIRDNNMD 1012

  Fly   626 PDEMLLHFSSLAMYMDGQLILRKARGLLHQYRQL 659
            ..:::..|:..|...|.|.|||.||.|:|:.:.|
  Rat  1013 FTDIIKFFNERAERHDAQEILRIARDLVHKVQML 1046

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBC1D16	NP_609403.2	TBC	387..618	CDD:214540	83/401 (21%)
Sgsm2	XP_006246802.1	RUN	42..189	CDD:280855
		PH_RUTBC	256..424	CDD:275431	31/187 (17%)
		TBC	<838..1006	CDD:214540	57/174 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810