Protein Alignment TBC1D16 and Rabgap1l

DIOPT Version :9

• Sequence 1: NP_609403.2
• Gene: TBC1D16 / 34431
• FlyBaseID: FBgn0032249
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: XP_006496938.1
• Gene: Rabgap1l / 29809
• MGIID: 1352507
• Length: 1051
• Species: Mus musculus
• Alignment Length: 856
• Identity: 169/856 - (19%)
• Similarity: 271/856 - (31%)
• Gaps: 317/856 - (37%)

  Fly     7 IKKASSFILGDERLDRKIDIAYEDNEILFCKNNVCIHPPTIARDESDILHNP-GYLTCTTKTFVD 70
            :|.||:   |||:|::.::....|:|    |....:  |...:..|:|...| |.:..:..|
Mouse    45 LKIASN---GDEQLEKAMEEILRDSE----KGQSGL--PVDCQGSSEISDCPFGDVPASQTT--- 97

  Fly    71 QYNSAKRPTLLLTWIPNSSLCKYTNLNADDCRGQCNPRSKSPD-------------SRNGYCHVT 122
                  :|.|.|...|::     |.::        .||..||.             :..|...|:
Mouse    98 ------KPPLQLILDPSN-----TEIS--------TPRPSSPSRFPEEDSVLFNKLTYLGCMKVS 143

  Fly   123 IPQTIQERDIREEDENAADMQELKNELQ-PLLGGQAASIDDLTALLKNNPITSVNI--TISNPQI 184
            .|        |.|.|....|..::...| |..         :|..:.|.|..||.|  ..||.:|
Mouse   144 SP--------RSEVEALRAMATMRASSQYPFA---------VTLYVPNVPEGSVRIIDQSSNVEI 191

  Fly   185 ---------------------------ENSNISQSFN-------------------CITIRPDSN 203
                                       |:|:.|:.|.                   |...:..|.
Mouse   192 ASFPIYKVLFCARGHDGTAESNCFAFTESSHGSEEFQIHVFSCEIKEAVSRILYSFCTAFKRSSR 256

  Fly   204 NCSDCTNGSGVGDG--PATDNPKWTTPELLAFKHNLEFPD---SGNSTPA--DRQKSAMKCRH-- 259
            ..||      |.|.  |..|:      ::..|..:||..:   .||.:|.  ||.|...|.:.
Mouse   257 QVSD------VKDSVIPTPDS------DVFTFSVSLEVKEDDGKGNFSPVPKDRDKFYFKIKQGI 309

  Fly   260 ---FSVDLSQMRSLRLFFNDDNCTSGQLVIASRESQYKILHF--------HYGGLDHLAQVLHQW 313
               ..:.:.|:.:..|..  :.| .|.|:...|..:...:|.        .|.|..::  :...|
Mouse   310 EKKVVITVQQLSNKELAI--ERC-FGMLLSPGRNVKNSDMHLLDMESMGKSYDGRAYV--ITGMW 369

  Fly   314 H----CFLHNITSETGQDK-------FDL-------PYRHFM--VCR------------------ 340
            :    .|| .:..||.:||       .|:       |.|..:  |.|
Mouse   370 NPNAPIFL-ALNEETPKDKRVYMTVAVDMVVTEVVEPVRFLLETVVRVYPANERFWYFSRKTFTE 433

  Fly   341 ---PEVKKSE-----------------------------------MHPDE--------------- 352
               ..:|:||                                   |.|.|
Mouse   434 TFFMRLKQSEGKGHSSAGDAIYEVVSLQRESDKEEPITPTSAGGPMSPQEDEAEEESDNELSSGT 498

  Fly   353 GDVKKITTN---FFYGTLLNEKGQIEDDLLLRKCVFF----GGLEKSLRKTVWPFLLKCYSFSST 410
            |||.|....   :.:|.||   |:..::|..|....|    .|:.::||..||..|..|:
Mouse   499 GDVSKDCPEKILYSWGELL---GRWHNNLGGRPKGLFTLVKSGVPEALRAEVWQLLAGCH----- 555

  Fly   411 FEDRAVLMDIKRQEYEEITRKRLYSMSPEQQIHFWKTVQIVVEKDVVRTDRTNPFFCGDDNPNTE 475
              |...::|    :|..:..|.             ...:.|:.:|:.||...:.:|........|
Mouse   556 --DNQEMLD----KYRILITKD-------------SAQESVITRDIHRTFPAHDYFKDTGGDGQE 601

  Fly   476 VMKNILLNFAVYNTGMSYSQGMSDLLAPVLCEVQNESETFWCFVGLM--------QRAFFVCTPT 532
            .:..|...::|::..:.|.||.| .||.||.....|.:.|...|.:|        .|..|
Mouse   602 SLYKICKAYSVFDEDIGYCQGQS-FLAAVLLLHMPEEQAFCVLVTIMYGYKLRDLYRNNF----- 660

  Fly   533 DRDVDHNLSYLRELIRIMLPHFYKH-----LEQHNDSMELLFCHRWLLLCFKREFTEAVVIRMWE 592
             .|:......|.:|::..||..|.|     ||.|      ::..:|.|..|..:|...:|..:.:
Mouse   661 -EDLHCKFYQLEKLMQEQLPDLYSHFCDLNLEAH------MYASQWFLTLFTAKFPLCMVFHIID 718

  Fly   593 ACWSNYLTDYFHLFLCLAIIAVYADDVVAQNLRPDEMLLHFSSLAMYMDGQLILR-----KARGL 652
            ......|...||  :.||::....:|:    |:.|     |.....:...||..|     .||.|
Mouse   719 LLLCEGLNIIFH--VALALLKTSKEDL----LQAD-----FEGALKFFRVQLPKRYRAEENARRL 772

  Fly   653 LHQYRQLPKIP 663
            :.|...: |:|
Mouse   773 MEQACNI-KVP 782

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBC1D16	NP_609403.2	TBC	387..618	CDD:214540	53/243 (22%)
Rabgap1l	XP_006496938.1	PTB_Rab6GAP	129..257	CDD:269922	24/144 (17%)
		DUF3694	290..421	CDD:372133	27/136 (20%)
		RabGAP-TBC	541..744	CDD:366170	53/245 (22%)
		Smc	<814..>1019	CDD:224117

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810