Protein Alignment TBC1D16 and tbc-18

DIOPT Version :9

• Sequence 1: NP_609403.2
• Gene: TBC1D16 / 34431
• FlyBaseID: FBgn0032249
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: NP_509421.2
• Gene: tbc-18 / 181091
• WormBaseID: WBGene00018281
• Length: 826
• Species: Caenorhabditis elegans
• Alignment Length: 328
• Identity: 70/328 - (21%)
• Similarity: 130/328 - (39%)
• Gaps: 76/328 - (23%)

  Fly   305 HLAQVL-HQWH-----CFLHNITSETGQDKFDLPYRHFMVCRPEVKKSEMHPDEGDVKKITTNFF 363
            ||::.| :..|     .:|.::..|.   |.|:.:.|  :..||:|...
 Worm    98 HLSEPLENSTHKLKLISYLQDVHKEV---KDDVLWSH--ILGPELKTDR---------------- 141

  Fly   364 YGTLLNEKGQIEDDLLLRKCVFFGGLEKSLRKTVWPFLLKCYSFSSTFEDRAVLMDIKRQEYEEI 428
            :..||.|                ||:..|:|..:||.|...               .|:|:..:.
 Worm   142 FEELLKE----------------GGIPHSMRPFLWPRLSGA---------------TKKQKDAKY 175

  Fly   429 TRKRLYSMSPEQQIHFWKTVQIVVEKDVVRTDRTNPFFCGDDNPNTEVMKNILLNFAVYNTGMSY 493
            |.:.:.....:.:    .::.:.:|:|::||...|..|...::...|.::.||...|.....:.|
 Worm   176 TYESVLQQCAQDK----PSIGVQIERDLLRTLPNNICFWKKNSEGIEALRRILKCVAFIYPDLGY 236

  Fly   494 SQGMSDLLAPVL--CEVQNESETFWCFVGLMQRA----FFVCTPTDRDVDHNLSYLRELIRIMLP 552
            .|||..::|.:|  |   :|..|||....|::..    |:..|......|..:|  |.|::..:|
 Worm   237 CQGMGVIVATLLLYC---SEETTFWMMTALIEDILPPNFYTQTLLGLQADERVS--RHLMKCHVP 296

  Fly   553 HFYKHLEQHNDSMELLFCHRWLLLCFKREFTEAVVIRMWEACWSNYLTDYFHLFLCLAIIAVYAD 617
            ...|.||.:...:.||.. .|||..|...|...|::|:|:..:.:...:.|.:.  ::|:.:...
 Worm   297 DLNKALEDYEVEVSLLTV-SWLLTLFGSVFRTRVMLRVWDFIFYSGGVNIFRVI--ISILKMKEQ 358

  Fly   618 DVV 620
            ::|
 Worm   359 EIV 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBC1D16	NP_609403.2	TBC	387..618	CDD:214540	54/236 (23%)
tbc-18	NP_509421.2	TBC	148..361	CDD:214540	55/255 (22%)
		SH3_SGSM3	528..580	CDD:212747
		RUN	607..765	CDD:280855

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810