DRSC/TRiP Functional Genomics Resources

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Protein Alignment TBC1D16 and Tbc1d15-17

DIOPT Version :10

Sequence 1:NP_609403.2 Gene:TBC1D16 / 34431 FlyBaseID:FBgn0032249 Length:702 Species:Drosophila melanogaster
Sequence 2:XP_061511086.1 Gene:Tbc1d15-17 / 1278047 VectorBaseID:AGAMI1_010828 Length:672 Species:Anopheles gambiae


Alignment Length:613 Identity:157/613 - (25%)
Similarity:252/613 - (41%) Gaps:163/613 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   199 RPDSNNCSDCTNGSGVGDGPATDNPKWTTPELLAFKHNLEFPDSGNSTPADRQKSAMKCRHFSVD 263
            :|.|..|...| .||.|..|::             :...|.|.:|..|     |:.:..|.|..|
Mosquito    84 QPASIACPTST-VSGTGSSPSS-------------RATSEEPATGAPT-----KAKLSIRVFLRD 129

  Fly   264 LSQMRS----LRLFFNDDNCTSGQLVIASRESQYKILHFHYGGLDHLAQVLHQWHCF-------- 316
            |..:.:    || |:|.|:            :.:.:..|.......|.|:|.::.|.        
Mosquito   130 LKGLETHKDELR-FYNHDH------------TVHSVYLFRQTSTSVLLQLLERFRCVRKSTHRKN 181

  Fly   317 LHNITSETGQDKF----------DL-------PYRHFM-----------VCRP--------EVKK 345
            .:....:..|||.          |:       ||...:           :.||        |::.
Mosquito   182 FYRCIDDPDQDKLQKSFSELNIADIRARPRPRPYMDMLSKLANVQQILPIHRPASQSTLPGELRL 246

  Fly   346 SEMH----------------------PDEGDVKKITTN-------------FFYGTLLNEK---G 372
            |.::                      .|.|:.....|.             ...||..:.|   |
Mosquito   247 SNLNARVQDAAADRHSTDESHGGVPVTDNGETNGTETRKLAPRPPVHRGLPLDAGTWEDVKCPNG 311

  Fly   373 QIEDDLLLRKCVFFGGLEKSLRKTVWPFLLKCYSFSSTFEDRAVLMDIKRQEYEEITRKRLYSMS 437
            .|.|...:::.:|.||:::.:|..||.:||....:..|.:.|......|.|||.::..:.| :|:
Mosquito   312 SISDPERVKEIIFRGGIKQDIRAEVWKYLLGLDVWEHTTQQRDERRAHKTQEYFQMKFQWL-TMT 375

  Fly   438 PEQQIHF--WKTVQIVVEKDVVRTDRTNPFFCGDDNPNTEVMKNILLNFAVYNTGMSYSQGMSDL 500
            |.|:.:|  ::..:..:||||.|||||..||.||||||...:::||:.:.:||..:.|.||||||
Mosquito   376 PTQEHNFTGYRERKCQIEKDVKRTDRTYEFFAGDDNPNLAKLQDILMTYVMYNFDLGYVQGMSDL 440

  Fly   501 LAPVLCEVQNESETFWCFVGLMQRAFFVCTPTDRDVDH-----NLSYLRELIRIMLPHFYKHLEQ 560
            |||:|..||||:|:||||||.|.:.|     .:.|:|.     .|.:||.|:..:....:.::.:
Mosquito   441 LAPILSLVQNEAESFWCFVGFMHKVF-----ANFDIDQKGMKLQLEHLRVLLSFVNERLFNYMRE 500

  Fly   561 HNDSMELLFCHRWLLLCFKREFTEAVVIRMWEACWSNYLTDYFHLFLCLAIIAVYADDVVAQNLR 625
             |.|..:.||.||||:.|||||:.:.::.:||..|:......||||:|:||:....|..:.....
Mosquito   501 -NQSENMYFCFRWLLVWFKREFSNSDIMHLWEVLWTGLPCPNFHLFVCVAILDQEMDVFIDGQFS 564

  Fly   626 PDEMLLHFSSLAMYMDGQLILRKARGLLHQYRQLPKIPCTLSGLCKRCGPGMWDSEHRPALECVG 690
            ..|:|.|.:.|:..::...:|.:|..:..|.:|      ||....|        ..|....:.:|
Mosquito   565 FTEILKHVNELSGNLNLAAVLEQAESIYLQVKQ------TLDAASK--------ESHHELRKIIG 615

  Fly   691 -----------------HSDDEKCSLSI 701
                             ..|:|...:||
Mosquito   616 EQLSSSEGGTTGNTDEDEEDEEDSCMSI 643

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TBC1D16NP_609403.2 TBC 387..618 CDD:214540 92/237 (39%)
Tbc1d15-17XP_061511086.1 None

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