Protein Alignment TBC1D16 and TBC1D16

DIOPT Version :10

• Sequence 1: NP_609403.2
• Gene: TBC1D16 / 34431
• FlyBaseID: FBgn0032249
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: XP_061511051.1
• Gene: TBC1D16 / 1270707
• VectorBaseID: AGAMI1_011942
• Length: 826
• Species: Anopheles gambiae
• Alignment Length: 842
• Identity: 488/842 - (57%)
• Similarity: 574/842 - (68%)
• Gaps: 156/842 - (18%)

  Fly     1 MPIGSIIKKASSFILG--DERLDRKIDIAYEDNEILFCKNNVCIHPPTIARDESDILHNPGYLTC 63
            |||.:|:|:|||:|||  |:..:...::.||||||||||||:|:|||.:.|.||||||.|||||.
Mosquito     1 MPIVNILKRASSYILGSDDDAEEGPGELVYEDNEILFCKNNICVHPPAVVRQESDILHYPGYLTV 65

  Fly    64 TTKTFVDQYNSAKRPTLLLTWIPNSSL--CKYTNLNADDCRGQCN-------------------- 106
            |||||:||||:||||||.|||||||:|  |..|..|....|...|
Mosquito    66 TTKTFIDQYNNAKRPTLFLTWIPNSTLRKCPSTVENVGLARAAANGVALSESKLKLHLQQLQPAP 130

  Fly   107 ------------------PRSKSP---------------------------DSRNGYCH-----V 121
                              |..::|                           ||::..|.     :
Mosquito   131 KGNGADRGAAGQPEKPTGPVGENPFTTTIKIANTNPFLEPYNETIAQSATSDSKSMNCSDYSETI 195

  Fly   122 TIPQTIQE-----------RD------------------------------------IREEDENA 139
            :|.....:           ||                                    :.||:|..
Mosquito   196 SISSNSDKASLCNSNDYDGRDDGPDDEDDVDEGCIVTSEAHHSTASVGGGDGAANDLLEEEEEEE 260

  Fly   140 ADMQELKNELQPLL---------GGQAASIDDLTALLKNNPITSVNITISNPQIENSNIS----- 190
            .:..|||.||||||         ||....:.....|...:.:|||||||::|.|:|.:||
Mosquito   261 GEDAELKTELQPLLEDGTKLSAAGGGTGKLHHHHKLPSQSSVTSVNITIASPHIQNVDISPPEAT 325

  Fly   191 ----QSFNCITIRPDSNNCSDCTNGSGVGDGPATDNPKWTTPELLAFKHNLEFPDSGNSTPADRQ 251
                :.|    :|..|...||            .:||.|.:|||||:||||.||:|.:::|...:
Mosquito   326 LPATERF----LRSLSITSSD------------ENNPNWMSPELLAYKHNLAFPESASASPIVSR 374

  Fly   252 KSAMKCRHFSVDLSQMRSLRLFFNDDNCTSGQLVIASRESQYKILHFHYGGLDHLAQVLHQWHCF 316
            |:.:|||.|||||||||:|||||||:.|||||||||||||||||||||:|||||||||||||||.
Mosquito   375 KAPLKCRRFSVDLSQMRALRLFFNDEQCTSGQLVIASRESQYKILHFHHGGLDHLAQVLHQWHCL 439

  Fly   317 LHNITSETGQDK-FDLPYRHFMVCRPEVKKSEMHPDEGDVKKITTNFFYGTLLNEKGQIEDDLLL 380
            ||||....|||: .::|||.||||||||:.:|:||:||.|.||||::||||||||:|||||||.|
Mosquito   440 LHNIKLAPGQDEPANVPYRQFMVCRPEVRPAELHPEEGKVSKITTDYFYGTLLNERGQIEDDLQL 504

  Fly   381 RKCVFFGGLEKSLRKTVWPFLLKCYSFSSTFEDRAVLMDIKRQEYEEITRKRLYSMSPEQQIHFW 445
            |||||||||::|||||||||||.|||..|||||||.|.:|:|||||||||:||||||||.|..||
Mosquito   505 RKCVFFGGLDRSLRKTVWPFLLHCYSTGSTFEDRAALGEIRRQEYEEITRRRLYSMSPEAQAQFW 569

  Fly   446 KTVQIVVEKDVVRTDRTNPFFCGDDNPNTEVMKNILLNFAVYNTGMSYSQGMSDLLAPVLCEVQN 510
            :|||.|:|||||||||.||||.||||||.:.|||||||:|.||.||||:|||||||||||||:::
Mosquito   570 RTVQCVIEKDVVRTDRGNPFFAGDDNPNIDTMKNILLNYAFYNPGMSYTQGMSDLLAPVLCEIKS 634

  Fly   511 ESETFWCFVGLMQRAFFVCTPTDRDVDHNLSYLRELIRIMLPHFYKHLEQHNDSMELLFCHRWLL 575
            |||||||||||||||.|||||||.|:|.||.|||||||:|:|:|||||::|.|:|||||||||:|
Mosquito   635 ESETFWCFVGLMQRAIFVCTPTDNDIDRNLCYLRELIRLMVPNFYKHLQKHADAMELLFCHRWIL 699

  Fly   576 LCFKREFTEAVVIRMWEACWSNYLTDYFHLFLCLAIIAVYADDVVAQNLRPDEMLLHFSSLAMYM 640
            |||||||||||.||||||||||||||||||||||||||||||||:||:||.||||||||||||||
Mosquito   700 LCFKREFTEAVAIRMWEACWSNYLTDYFHLFLCLAIIAVYADDVIAQDLRTDEMLLHFSSLAMYM 764

  Fly   641 DGQLILRKARGLLHQYRQLPKIPCTLSGLCKRCGPGMWDSEHRPALECVGHSDDEKCSLSID 702
            |||||||||||||||:||.|||||||||||||||||||||.|.|::||:||.|.|.|:|::|
Mosquito   765 DGQLILRKARGLLHQFRQYPKIPCTLSGLCKRCGPGMWDSGHHPSIECIGHLDHETCALAMD 826

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBC1D16	NP_609403.2	TBC	387..618	CDD:214540	188/230 (82%)
TBC1D16	XP_061511051.1	None