DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bug22 and CFAP20

DIOPT Version :9

Sequence 1:	NP_609402.1	Gene:	Bug22 / 34429	FlyBaseID:	FBgn0032248	Length:	199	Species:	Drosophila melanogaster
Sequence 2:	NP_037374.1	Gene:	CFAP20 / 29105	HGNCID:	29523	Length:	193	Species:	Homo sapiens

Alignment Length:	193	Identity:	178/193 - (92%)
Similarity:	187/193 - (96%)	Gaps:	0/193 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFKNTFQSGFLSILYSIGSKPLQLWDKKVRNGHIKRITDNDIQSLVLEIVGTNVSTTFITCPADP 65
            |||||||||||||||||||||||:|||||||||||||||||||||||||.|||||||:|||||||
Human     1 MFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEIEGTNVSTTYITCPADP 65

  Fly    66 KKTLGIKLPFLVMIIKNMKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPFICTMPMRLDEGWN 130
            |||||||||||||||||:|||||||||||||||||||||||||||||||||||||||||||:|||
Human    66 KKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPFICTMPMRLDDGWN 130

  Fly   131 QIQFNLSDFTRRAYGTNYVETLRVQIHANCRIRRVYFSDRLYSEDELPPEFKLFLPIQKPVQK 193
            ||||||.|||||||||||:|||||||||||||||||||||||||||||.||||:||:|...::
Human   131 QIQFNLLDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDELPAEFKLYLPVQNKAKQ 193

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bug22	NP_609402.1	DUF667	1..185	CDD:398611	175/183 (96%)
CFAP20	NP_037374.1	DUF667	1..185	CDD:398611	175/183 (96%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156664
Domainoid	1	1.000	362	1.000	Domainoid score	I952
eggNOG	1	0.900	-	-		E1_KOG3213
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H7350
Inparanoid	1	1.050	370	1.000	Inparanoid score	I2137
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56333
OrthoDB	1	1.010	-	-		D1213295at2759
OrthoFinder	1	1.000	-	-		FOG0005006
OrthoInspector	1	1.000	-	-		oto91196
orthoMCL	1	0.900	-	-		OOG6_102689
Panther	1	1.100	-	-	LDO	PTHR12458
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2463
SonicParanoid	1	1.000	-	-		X4654
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800