Protein Alignment CG5188 and MAP1

DIOPT Version :10

• Sequence 1: NP_609401.2
• Gene: CG5188 / 34428
• FlyBaseID: FBgn0032247
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_013345.1
• Gene: MAP1 / 850945
• SGDID: S000004234
• Length: 387
• Species: Saccharomyces cerevisiae
• Alignment Length: 297
• Identity: 117/297 - (39%)
• Similarity: 171/297 - (57%)
• Gaps: 16/297 - (5%)

  Fly    24 GKVKGDTGKYEQIVSTGQVSPERFVPEEIKKPAYYFKNMP----PGNTLGSPEIKSQVQIDAMRL 84
            ||||          ::..::|.|:|||:|.||.:....:|    ..:.|.:..|..:.||..:|.
Yeast    86 GKVK----------ASYPLTPRRYVPEDIPKPDWAANGLPVSEQRNDRLNNIPIYKKDQIKKIRK 140

  Fly    85 SGRLAARILRECGKLATVGTTTDQIDAFAHERILESKAYPSPLRYAGFPKSICTSINNIACHGIP 149
            :..|...:|.........|.|||::|...|...::..||||||.|..||||:|||:|.:.|||:|
Yeast   141 ACMLGREVLDIAAAHVRPGITTDELDEIVHNETIKRGAYPSPLNYYNFPKSLCTSVNEVICHGVP 205

  Fly   150 DDRQLADGDIINIDVTVFLNGYHGDCSETFRVG-NVDERGGFLVEATKSCLDQCISLCGPGVEFN 213
            |...|.:|||:|:||:::..|||.|.:||:.|| |:.:......|.::.||...|.:|.||..|.
Yeast   206 DKTVLKEGDIVNLDVSLYYQGYHADLNETYYVGENISKEALNTTETSRECLKLAIKMCKPGTTFQ 270

  Fly   214 EIGKFIDRYCDEHDLASIAAFIGHGIGSYFHGPPEILHY-YNEIPGKMQPGMTFTIEPILSLGGA 277
            |:|..|:::..|:..:.:..:.|||:|.:||..|.|.|| .|..||.|:|||.|||||:::.|..
Yeast   271 ELGDHIEKHATENKCSVVRTYCGHGVGEFFHCSPNIPHYAKNRTPGVMKPGMVFTIEPMINEGTW 335

  Fly   278 EIAVLQDGWTAISLDGARSAQFEHTILITETGTEILT 314
            :.....|.||:.:.||..|||||||:|:||.|.||||
Yeast   336 KDMTWPDDWTSTTQDGKLSAQFEHTLLVTEHGVEILT 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5188	NP_609401.2	MetAP1	79..315	CDD:238519	101/238 (42%)
MAP1	NP_013345.1	APP_MetAP	23..379	CDD:469704	117/297 (39%)