DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5188 and MAP1B

DIOPT Version :9

Sequence 1:	NP_609401.2	Gene:	CG5188 / 34428	FlyBaseID:	FBgn0032247	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_189202.1	Gene:	MAP1B / 822165	AraportID:	AT3G25740	Length:	344	Species:	Arabidopsis thaliana

Alignment Length:	314	Identity:	139/314 - (44%)
Similarity:	182/314 - (57%)	Gaps:	32/314 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 GKVKGDT---GKYEQIVST-----------GQVSPERFVPEEIKKPAYYFKNMPPGNTLGSPEIK 74
            ||.|..:   .:.:|:.||           |.|||...||:.|.||.|.       .:...|||.
plant    37 GKKKSSSLRIKRIQQLQSTLEDRINPPLVCGTVSPRLSVPDHILKPLYV-------ESSKVPEIS 94

  Fly    75 SQVQID------AMRLSGRLAARILRECGKLATVGTTTDQIDAFAHERILESKAYPSPLRYAGFP 133
            |::||.      .|:.:..||||:|...|.|.....|||:||...|:.::|..||||||.|.|||
plant    95 SELQIPDSIGIVKMKKACELAARVLDYAGTLVRPFVTTDEIDKAVHQMVIEFGAYPSPLGYGGFP 159

  Fly   134 KSICTSINNIACHGIPDDRQLADGDIINIDVTVFLNGYHGDCSETFRVGNVDERGGFLVEATKSC 198
            ||:|||:|....|||||.|.|.:||||||||.|:|:|||||.|:||..|:|:.....||:.|:.|
plant   160 KSVCTSVNECMFHGIPDSRPLQNGDIINIDVAVYLDGYHGDTSKTFLCGDVNGSLKQLVKVTEEC 224

  Fly   199 LDQCISLCGPGVEFNEIGKFIDRYCDEHDLASIAAFIGHGIGSYFHGPPEI-LH--YYNEIPGKM 260
            |::.||:|..|..|.:|||.|..:..::.. ::..|||||:|:..|..|.| ||  |..|:. .|
plant   225 LEKGISVCKDGASFKQIGKIISEHAAKYGY-NMERFIGHGVGTVLHSEPLIYLHSNYDYELE-YM 287

  Fly   261 QPGMTFTIEPILSLGGAEIAVLQDGWTAISLDGARSAQFEHTILITETGTEILT 314
            ..|.|||:||||::|..|.....|.||.::.||..:||||||||||.||.||||
plant   288 IEGQTFTLEPILTIGTTEFVTWPDKWTIVTADGGPAAQFEHTILITTTGAEILT 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5188	NP_609401.2	MetAP1	79..315	CDD:238519	118/245 (48%)
MAP1B	NP_189202.1	MetAP1	105..341	CDD:238519	115/237 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	265	1.000	Domainoid score	I460
eggNOG	1	0.900	-	-		E1_COG0024
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	295	1.000	Inparanoid score	I809
OMA	1	1.010	-	-		QHG54721
OrthoDB	1	1.010	-	-		D1002357at2759
OrthoFinder	1	1.000	-	-		FOG0005461
OrthoInspector	1	1.000	-	-		otm2437
orthoMCL	1	0.900	-	-		OOG6_100342
Panther	1	1.100	-	-	O	PTHR43330
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3885
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840