Protein Alignment CG5188 and Metap1

DIOPT Version :9

• Sequence 1: NP_609401.2
• Gene: CG5188 / 34428
• FlyBaseID: FBgn0032247
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_780433.1
• Gene: Metap1 / 75624
• MGIID: 1922874
• Length: 386
• Species: Mus musculus
• Alignment Length: 327
• Identity: 135/327 - (41%)
• Similarity: 187/327 - (57%)
• Gaps: 20/327 - (6%)

  Fly     6 LLNSLMRQKTTARNLFQFGKVKGD--TGKYEQIVSTGQVSPE------RFVPEEIKKPAYYFKNM 62
            ||:...:.:...|.:..: .|:||  |..:.....||::.|.      |.||..|::|.|  .:.
Mouse    50 LLHKKAKDEKAKREVCSW-TVEGDVNTDPWAGYRYTGKLRPHYPLMPTRPVPSYIQRPDY--ADH 111

  Fly    63 PPGNT------LGSPEIK--SQVQIDAMRLSGRLAARILRECGKLATVGTTTDQIDAFAHERILE 119
            |.|.:      .|:.:||  |...|:.|||..|||..:|.....:...|.||::||...|...:.
Mouse   112 PLGMSESEQALKGTSQIKLLSSEDIEGMRLVCRLAREVLDIAAGMIKAGVTTEEIDHAVHLACIA 176

  Fly   120 SKAYPSPLRYAGFPKSICTSINNIACHGIPDDRQLADGDIINIDVTVFLNGYHGDCSETFRVGNV 184
            ...|||||.|..||||.|||:|.:.||||||.|.|.:|||:|:|:|::.||||||.:|||.||:|
Mouse   177 RNCYPSPLNYYNFPKSCCTSVNEVICHGIPDRRPLQEGDIVNVDITLYRNGYHGDLNETFFVGDV 241

  Fly   185 DERGGFLVEATKSCLDQCISLCGPGVEFNEIGKFIDRYCDEHDLASIAAFIGHGIGSYFHGPPEI 249
            ||....||:.|..||.|.|....|||.:.|:|..|.::...:..:.:.::.||||...||..|.:
Mouse   242 DEGARKLVQTTYECLMQAIDAVKPGVRYRELGNIIQKHAQANGFSVVRSYCGHGIHKLFHTAPNV 306

  Fly   250 LHY-YNEIPGKMQPGMTFTIEPILSLGGAEIAVLQDGWTAISLDGARSAQFEHTILITETGTEIL 313
            .|| .|:..|.|:.|..|||||::..||.:.....|||||::.||.||||||||:|:|:||.|||
Mouse   307 PHYAKNKAVGVMKSGHVFTIEPMICEGGWQDETWPDGWTAVTRDGKRSAQFEHTLLVTDTGCEIL 371

  Fly   314 TR 315
            ||
Mouse   372 TR 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5188	NP_609401.2	MetAP1	79..315	CDD:238519	111/236 (47%)
Metap1	NP_780433.1	Zinc finger-like, important for proper ribosome association. /evidence=ECO:0000255|HAMAP-Rule:MF_03174	9..52		1/1 (100%)
		APP_MetAP	14..382	CDD:320876	135/327 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1002357at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100342
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.720