DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5188 and fma1

DIOPT Version :9

Sequence 1:	NP_609401.2	Gene:	CG5188 / 34428	FlyBaseID:	FBgn0032247	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_596097.1	Gene:	fma1 / 2540928	PomBaseID:	SPBC3E7.10	Length:	379	Species:	Schizosaccharomyces pombe

Alignment Length:	284	Identity:	121/284 - (42%)
Similarity:	166/284 - (58%)	Gaps:	11/284 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 VSPERFVPEEIKKPAYYFKNMPPGNTLGSPEIK----SQVQIDAMRLSGRLAARILRECGKLATV 102
            :||.|.||..||:|.|....:.....:.....|    :..:.:.||...||...:|.........
pombe    84 LSPIRKVPPHIKRPDYAKTGVSRSEQIEGRSFKLKRLTPKEQEGMRKVCRLGREVLDAAAAAVRP 148

  Fly   103 GTTTDQIDAFAHERILESKAYPSPLRYAGFPKSICTSINNIACHGIPDDRQLADGDIINIDVTVF 167
            |||||::|:..|...:|...:||.|.|..||||:|||:|.|.||||||.|.|.||||:||||:::
pombe   149 GTTTDELDSIVHNACIERDCFPSTLNYYAFPKSVCTSVNEIICHGIPDQRPLEDGDIVNIDVSLY 213

  Fly   168 LNGYHGDCSETFRVGNVDERGG---FLVEATKSCLDQCISLCGPGVEFNEIGKFIDRYCD---EH 226
            .||:|||.:||:.||:..:...   .|||.|:..||:.|:...|||.|.|.|..|:::.:   |.
pombe   214 HNGFHGDLNETYYVGDKAKANPDLVCLVENTRIALDKAIAAVKPGVLFQEFGNIIEKHTNSITEK 278

  Fly   227 DLASIAAFIGHGIGSYFHGPPEILHY-YNEIPGKMQPGMTFTIEPILSLGGAEIAVLQDGWTAIS 290
            .::.:..:.||||...||..|.|.|| :|:.||..:|||||||||:|:||.|......|.||:.:
pombe   279 QISVVRTYCGHGINQLFHCSPSIPHYSHNKAPGIARPGMTFTIEPMLTLGPARDITWPDDWTSST 343

  Fly   291 LDGARSAQFEHTILITETGTEILT 314
            ..|..|||||||:|:||||.|:||
pombe   344 ASGRCSAQFEHTLLVTETGCEVLT 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5188	NP_609401.2	MetAP1	79..315	CDD:238519	111/243 (46%)
fma1	NP_596097.1	PLN03158	1..374	CDD:215607	121/284 (43%)
		zf-C6H2	14..53	CDD:292429
		MetAP1	126..367	CDD:238519	109/240 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100342
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.710