Protein Alignment CG5188 and METAP1D

DIOPT Version :10

• Sequence 1: NP_609401.2
• Gene: CG5188 / 34428
• FlyBaseID: FBgn0032247
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: XP_047299826.1
• Gene: METAP1D / 254042
• HGNCID: 32583
• Length: 351
• Species: Homo sapiens
• Alignment Length: 315
• Identity: 152/315 - (48%)
• Similarity: 194/315 - (61%)
• Gaps: 13/315 - (4%)

  Fly     7 LNSLMRQKTTA----RNLFQFGKVKGDTGKYEQIVSTGQVSPERFVPEEIKKPAYYFKNMPP--G 65
            ||.:...|.::    ||.| |.:.:..:   ..||....||....||:.||||.|....:.|  |
Human    39 LNHIYLHKQSSSQQRRNFF-FRRQRDIS---HSIVLPAAVSSAHPVPKHIKKPDYVTTGIVPDWG 99

  Fly    66 NTLGSPEIKSQVQIDAMRLSGRLAARILRECGKLATVGTTTDQIDAFAHERILESKAYPSPLRYA 130
            :::   |:|::.||..:..:.:||..:|...||...|..||::|||..|..|:...||||||.|.
Human   100 DSI---EVKNEDQIQGLHQACQLARHVLLLAGKSLKVDMTTEEIDALVHREIISHNAYPSPLGYG 161

  Fly   131 GFPKSICTSINNIACHGIPDDRQLADGDIINIDVTVFLNGYHGDCSETFRVGNVDERGGFLVEAT 195
            |||||:|||:||:.||||||.|.|.|||||||||||:.||||||.||||.||||||.|..|||..
Human   162 GFPKSVCTSVNNVLCHGIPDSRPLQDGDIINIDVTVYYNGYHGDTSETFLVGNVDECGKKLVEVA 226

  Fly   196 KSCLDQCISLCGPGVEFNEIGKFIDRYCDEHDLASIAAFIGHGIGSYFHGPPEILHYYNEIPGKM 260
            :.|.|:.|:.|..|..|:.||..|.....::.......|:||||||||||.|||.|:.|:....|
Human   227 RRCRDEAIAACRAGAPFSVIGNTISHITHQNGFQVCPHFVGHGIGSYFHGHPEIWHHANDSDLPM 291

  Fly   261 QPGMTFTIEPILSLGGAEIAVLQDGWTAISLDGARSAQFEHTILITETGTEILTR 315
            :.||.||||||::.|..|..||:|.||.:|||..||||||||:|||..|.:|||:
Human   292 EEGMAFTIEPIITEGSPEFKVLEDAWTVVSLDNQRSAQFEHTVLITSRGAQILTK 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5188	NP_609401.2	MetAP1	79..315	CDD:238519	128/235 (54%)
METAP1D	XP_047299826.1	MetAP1	110..346	CDD:238519	128/235 (54%)