DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5188 and map-1

DIOPT Version :9

Sequence 1:	NP_609401.2	Gene:	CG5188 / 34428	FlyBaseID:	FBgn0032247	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_500396.2	Gene:	map-1 / 177128	WormBaseID:	WBGene00003129	Length:	371	Species:	Caenorhabditis elegans

Alignment Length:	286	Identity:	122/286 - (42%)
Similarity:	171/286 - (59%)	Gaps:	12/286 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 GQVSPERFVPEEIKKPAYYFKNMPPGNTLGSPEIKSQVQI--------DAMRLSGRLAARILREC 96
            |:|:..|.||:.|.:|.|...  |.|.:|...:.||:..|        :.::::.:|....|.|.
Worm    72 GRVTDRRPVPDHIPRPDYALH--PQGVSLEERQSKSERVIKVLTDEEKEGLKVACKLGRECLNEA 134

  Fly    97 GKLATVGTTTDQIDAFAHERILESKAYPSPLRYAGFPKSICTSINNIACHGIPDDRQLADGDIIN 161
            .|....|.||::||...||..:|...|||||.|..||||.|||:|.:.||||||.|:|.:||:.|
Worm   135 AKACGPGVTTEEIDRVVHEAAIERDCYPSPLGYYKFPKSCCTSVNEVICHGIPDMRKLENGDLCN 199

  Fly   162 IDVTVFLNGYHGDCSETFRVGN-VDERGGFLVEATKSCLDQCISLCGPGVEFNEIGKFIDRYCDE 225
            :||||:..|:|||.:|||.||: |||....||:.|..||.|.|::..|||:|.|||..|.::.:.
Worm   200 VDVTVYHRGFHGDLNETFLVGDKVDEESRKLVKVTFECLQQAIAIVKPGVKFREIGNVIQKHANA 264

  Fly   226 HDLASIAAFIGHGIGSYFHGPPEILHY-YNEIPGKMQPGMTFTIEPILSLGGAEIAVLQDGWTAI 289
            :..:.:..:.||||...||..|.:.|| .|...|.|:.|.:|||||:::.|........|.|||:
Worm   265 NGFSVVKGYCGHGIHRLFHTAPNVPHYAKNNATGVMKAGNSFTIEPMINAGTYHDDKWPDDWTAV 329

  Fly   290 SLDGARSAQFEHTILITETGTEILTR 315
            :.||.||||||.|:|:|:||.||||:
Worm   330 TRDGRRSAQFEQTLLVTDTGCEILTK 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5188	NP_609401.2	MetAP1	79..315	CDD:238519	108/245 (44%)
map-1	NP_500396.2	PLN03158	9..356	CDD:215607	122/286 (43%)
		zf-C6H2	11..50	CDD:292429
		MetAP1	118..355	CDD:238519	107/236 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1002357at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100342
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820