DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment KdelR and kdelr2b

DIOPT Version :9

Sequence 1:	NP_477296.1	Gene:	KdelR / 34427	FlyBaseID:	FBgn0267330	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	NP_997860.1	Gene:	kdelr2b / 325464	ZFINID:	ZDB-GENE-030131-4189	Length:	212	Species:	Danio rerio

Alignment Length:	212	Identity:	151/212 - (71%)
Similarity:	188/212 - (88%)	Gaps:	0/212 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MNIFRFAGDLSHVFAIIILLLKIWKTRSCAGISGKSQILFAVVYLTRYLDLFTTYVSLYNSVMKV 65
            ||:||..|||||:.|||||||||||:|||||||||||||||:|:.||||||.|:::||||:.|||
Zfish     1 MNLFRLTGDLSHLAAIIILLLKIWKSRSCAGISGKSQILFALVFTTRYLDLLTSFISLYNTSMKV 65

  Fly    66 LFLATSGATVYLMYVKFKATYDHNHDSFRIEFLLVPCALLSLVINHEFTVMEVLWTFSIYLESVA 130
            :::|.:.|||||:|.|||||||.|||:||:|||:||...|:.::||:|:.:|:|||||||||||:
Zfish    66 IYIACAYATVYLIYAKFKATYDGNHDTFRVEFLVVPVGGLAFLVNHDFSPLEILWTFSIYLESVS 130

  Fly   131 ILPQLFLVSRTGEAESITSHYLFALGSYRALYLLNWVYRYMVESHYDLIAIFAGVVQTVLYCDFF 195
            ||||||::|:|||||:||:||||.||.||||||.||::|:..|..:|:|||.||||||:||||||
Zfish   131 ILPQLFMISKTGEAETITTHYLFFLGLYRALYLFNWIWRFYFEGFFDMIAIVAGVVQTILYCDFF 195

  Fly   196 YLYITKVLKGKKLQLPA 212
            |||:|||||||||.|||
Zfish   196 YLYVTKVLKGKKLSLPA 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
KdelR	NP_477296.1	ER_lumen_recept	28..169	CDD:395652	97/140 (69%)
kdelr2b	NP_997860.1	ER_lumen_recept	28..169	CDD:279187	97/140 (69%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579960
Domainoid	1	1.000	217	1.000	Domainoid score	I2614
eggNOG	1	0.900	-	-		E1_COG5196
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	327	1.000	Inparanoid score	I2450
OMA	1	1.010	-	-		QHG53919
OrthoDB	1	1.010	-	-		D1186269at2759
OrthoFinder	1	1.000	-	-		FOG0000906
OrthoInspector	1	1.000	-	-		otm25450
orthoMCL	1	0.900	-	-		OOG6_101087
Panther	1	1.100	-	-	LDO	PTHR10585
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R403
SonicParanoid	1	1.000	-	-		X521
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.800