DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment KdelR and Kdelr3

DIOPT Version :9

Sequence 1:	NP_477296.1	Gene:	KdelR / 34427	FlyBaseID:	FBgn0267330	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	NP_001121018.1	Gene:	Kdelr3 / 315131	RGDID:	1311536	Length:	214	Species:	Rattus norvegicus

Alignment Length:	211	Identity:	137/211 - (64%)
Similarity:	179/211 - (84%)	Gaps:	0/211 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MNIFRFAGDLSHVFAIIILLLKIWKTRSCAGISGKSQILFAVVYLTRYLDLFTTYVSLYNSVMKV 65
            ||:||..|||||:.|:|:||:|||:::||||||||||||||:|:.|||||||:.::|:||:||||
  Rat     1 MNVFRILGDLSHLLAMILLLVKIWRSKSCAGISGKSQILFALVFTTRYLDLFSNFISIYNTVMKV 65

  Fly    66 LFLATSGATVYLMYVKFKATYDHNHDSFRIEFLLVPCALLSLVINHEFTVMEVLWTFSIYLESVA 130
            :||..:..|||::|.||:.|:|..:|:||:|||:||...||.::|:.:..||:||||||||||||
  Rat    66 VFLLCAYVTVYMIYWKFRKTFDIENDTFRLEFLVVPVTGLSFLVNYSYAPMEILWTFSIYLESVA 130

  Fly   131 ILPQLFLVSRTGEAESITSHYLFALGSYRALYLLNWVYRYMVESHYDLIAIFAGVVQTVLYCDFF 195
            ||||||::|:|||||:||:||||.||.||.|||.||:.||..|:.||.|::.:|||||:.|||||
  Rat   131 ILPQLFMISKTGEAETITTHYLFFLGLYRLLYLANWIRRYQTENFYDQISVVSGVVQTIFYCDFF 195

  Fly   196 YLYITKVLKGKKLQLP 211
            |||:|||||||||.||
  Rat   196 YLYVTKVLKGKKLSLP 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
KdelR	NP_477296.1	ER_lumen_recept	28..169	CDD:395652	91/140 (65%)
Kdelr3	NP_001121018.1	ER_lumen_recept	28..169	CDD:395652	91/140 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340111
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53919
OrthoDB	1	1.010	-	-		D1186269at2759
OrthoFinder	1	1.000	-	-		FOG0000906
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101087
Panther	1	1.100	-	-	O	PTHR10585
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X521
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.860