DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SmB and snrpb

DIOPT Version :9

Sequence 1:	NP_001188780.1	Gene:	SmB / 34426	FlyBaseID:	FBgn0262601	Length:	199	Species:	Drosophila melanogaster
Sequence 2:	NP_991230.1	Gene:	snrpb / 402966	ZFINID:	ZDB-GENE-040426-1819	Length:	239	Species:	Danio rerio

Alignment Length:	233	Identity:	138/233 - (59%)
Similarity:	159/233 - (68%)	Gaps:	39/233 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTIGKNNKMIQHLNYRVRIVLQDSRTFIGTFKAFDKHMNLILGDCEEFRKIRSKNSKVPEREEKR 65
            ||:||::||:||::||:|.:|||.|.||||||||||||||||.||:|||||:.||||.|||||||
Zfish     1 MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQPEREEKR 65

  Fly    66 VLGFVLLRGENIVSLTVEGPPPPEEGLPRVPIPGAAPGPGIGRVAGRGMPIN--LSAVPAGLQGP 128
            |||.|||||||:||:|||||||.:.|:.|||:.|.|.|||:||.||||:|..  ::..||||.||
Zfish    66 VLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGVAGGPGVGRAAGRGVPAGAPMAQAPAGLAGP 130

  Fly   129 VRGVGGPAQQHMAPMGRGV-----------------------PRAPM-MGAPPPGMI---PGGMP 166
            |||||||:||.|.|.|||.                       |..|| .|||||||:   ||..|
Zfish   131 VRGVGGPSQQVMTPQGRGTVAAAAAGASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRP 195

  Fly   167 SM--PGNM--GRGA-----PPPMRGPPPSMIRGAPPPG 195
            .|  |..|  ||||     ||.||.|||.| ||.||||
Zfish   196 PMGPPMGMPPGRGAPMGMPPPGMRPPPPGM-RGPPPPG 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SmB	NP_001188780.1	Sm_B	5..82	CDD:212464	58/76 (76%)
snrpb	NP_991230.1	Sm_B	5..83	CDD:212464	59/77 (77%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574589
Domainoid	1	1.000	126	1.000	Domainoid score	I5385
eggNOG	1	0.900	-	-		E1_COG1958
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68297
Inparanoid	1	1.050	254	1.000	Inparanoid score	I3165
OMA	1	1.010	-	-		QHG54849
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002776
OrthoInspector	1	1.000	-	-		oto40080
orthoMCL	1	0.900	-	-		OOG6_101868
Panther	1	1.100	-	-	LDO	PTHR10701
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1254
SonicParanoid	1	1.000	-	-		X2167
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.790