DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SmB and Snrpn

DIOPT Version :9

Sequence 1:	NP_001188780.1	Gene:	SmB / 34426	FlyBaseID:	FBgn0262601	Length:	199	Species:	Drosophila melanogaster
Sequence 2:	NP_001076430.1	Gene:	Snrpn / 20646	MGIID:	98347	Length:	240	Species:	Mus musculus

Alignment Length:	235	Identity:	132/235 - (56%)
Similarity:	155/235 - (65%)	Gaps:	41/235 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTIGKNNKMIQHLNYRVRIVLQDSRTFIGTFKAFDKHMNLILGDCEEFRKIRSKNSKVPEREEKR 65
            ||:||::||:||::||:|.:|||.|.||||||||||||||||.||:|||||:.||:|.|||||||
Mouse     1 MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPEREEKR 65

  Fly    66 VLGFVLLRGENIVSLTVEGPPPPEEGLPRVPIPGAAPGPGIGRVAGRGMP--INLSAVPAGLQGP 128
            |||.|||||||:||:|||||||.:.|:.|||:.|||.|||:||.||||:|  :.:...||||.||
Mouse    66 VLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGP 130

  Fly   129 VRGVGGPAQQHMAPMGRG------------------------------VPRA---PMMGAPPPGM 160
            |||||||:||.|.|.|||                              |.||   |.:.||||||
Mouse   131 VRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPPPGM 195

  Fly   161 IPG-----GMPSMPGNMGRGAPPPMRGPPPSMIRGAPPPG 195
            .|.     |:|...|. ..|.|||...|||..|||.||||
Mouse   196 RPPMGPPIGLPPARGT-PIGMPPPGMRPPPPGIRGPPPPG 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SmB	NP_001188780.1	Sm_B	5..82	CDD:212464	57/76 (75%)
Snrpn	NP_001076430.1	Sm_B	5..83	CDD:212464	58/77 (75%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	163..240		28/73 (38%)
		Repeat-rich region	175..236		28/61 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	124	1.000	Domainoid score	I5497
eggNOG	1	0.900	-	-		E1_COG1958
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68297
Inparanoid	1	1.050	251	1.000	Inparanoid score	I3202
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54849
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002776
OrthoInspector	1	1.000	-	-		otm43772
orthoMCL	1	0.900	-	-		OOG6_101868
Panther	1	1.100	-	-	LDO	PTHR10701
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1254
SonicParanoid	1	1.000	-	-		X2167
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.860