Protein Alignment Wdfy2 and Gga1

DIOPT Version :10

• Sequence 1: NP_609400.1
• Gene: Wdfy2 / 34425
• FlyBaseID: FBgn0032246
• Length: 408
• Species: Drosophila melanogaster
• Sequence 2: NP_666041.1
• Gene: Gga1 / 106039
• MGIID: 2146207
• Length: 635
• Species: Mus musculus
• Alignment Length: 120
• Identity: 24/120 - (20%)
• Similarity: 46/120 - (38%)
• Gaps: 35/120 - (29%)

  Fly     7 PAQRTNNDRFNTSKKPELLSKLEGSS--DDVNAAILIPGENGVISVSDDKTVRVWLKRDSGQYWP 69
            |..|..|..|...:|.::|::|..||  :|:.||              :|.::..::.|..:
Mouse   160 PPPRPKNVIFEDEEKSKMLARLLKSSHPEDLRAA--------------NKLIKEMVQEDQKR--- 207

  Fly    70 SICQYMPSGCTAIEYVSES----RHLYVGQENGTVTQYALSED--------CNRL 112
              .:.:.....|||.|:.:    ..:.:....|..:  :.|||        |.|:
Mouse   208 --MEKISKRVNAIEEVNNNVKLLTEMVMSHSQGAAS--SSSEDLMKELYQRCERM 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wdfy2	NP_609400.1	WD40	24..279	CDD:475233	19/103 (18%)
		WD40 repeat	35..72	CDD:293791	4/36 (11%)
		WD40 repeat	80..117	CDD:293791	10/45 (22%)
		WD40 repeat	125..161	CDD:293791
		WD40 repeat	166..205	CDD:293791
		WD40 repeat	211..248	CDD:293791
		WD40 repeat	253..283	CDD:293791
		FYVE_WDFY1_like	287..356	CDD:277258
		WD40 repeat	324..371	CDD:293791
Gga1	NP_666041.1	VHS_GGA1	9..147	CDD:340806
		Interaction with ARF3. /evidence=ECO:0000250	114..273		24/120 (20%)
		GGA_N-GAT	169..207	CDD:465702	11/51 (22%)
		GAT_GGA1_GGA2	210..297	CDD:410586	10/51 (20%)
		Unstructured hinge	299..505
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	305..349
		Autoinhibitory. /evidence=ECO:0000250	357..361
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	362..422
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	455..490
		Alpha_adaptinC2	513..627	CDD:197886